CITE3_CHICK
ID CITE3_CHICK Reviewed; 205 AA.
AC Q9I8K7;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Cbp/p300-interacting transactivator 3;
DE Short=cCITED3;
GN Name=CITED3;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RC TISSUE=Urogenital system;
RX PubMed=10906483; DOI=10.1016/s0925-4773(00)00362-2;
RA Andrews J.E., O'Neill M.J., Binder M., Shioda T., Sinclair A.H.;
RT "Isolation and expression of a novel member of the CITED family.";
RL Mech. Dev. 95:305-308(2000).
RN [2]
RP FUNCTION.
RX PubMed=11581164; DOI=10.1101/gad.906301;
RA Yahata T., Shao W., Endoh H., Hur J., Coser K.R., Sun H., Ueda Y., Kato S.,
RA Isselbacher K.J., Brown M., Shioda T.;
RT "Selective coactivation of estrogen-dependent transcription by CITED1
RT CBP/p300-binding protein.";
RL Genes Dev. 15:2598-2612(2001).
CC -!- FUNCTION: Acts as transcriptional coactivator. Enhances estrogen-
CC dependent transactivation mediated by estrogen receptors.
CC {ECO:0000269|PubMed:11581164}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the pre-somitic mesoderm, mesonephric
CC tubules, Wolfan ducts and collecting tubules of the developing
CC urogenital system. Also expressed in the cranial sensory ganglia,
CC pineal gland and eye. {ECO:0000269|PubMed:10906483}.
CC -!- SIMILARITY: Belongs to the CITED family. {ECO:0000305}.
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DR EMBL; AF261079; AAF76148.1; -; mRNA.
DR RefSeq; NP_990049.1; NM_204718.2.
DR AlphaFoldDB; Q9I8K7; -.
DR STRING; 9031.ENSGALP00000000958; -.
DR PaxDb; Q9I8K7; -.
DR Ensembl; ENSGALT00000000960; ENSGALP00000000958; ENSGALG00000000678.
DR Ensembl; ENSGALT00000106831; ENSGALP00000074126; ENSGALG00000000678.
DR GeneID; 395465; -.
DR KEGG; gga:395465; -.
DR CTD; 163732; -.
DR VEuPathDB; HostDB:geneid_395465; -.
DR eggNOG; ENOG502RY5J; Eukaryota.
DR GeneTree; ENSGT00530000063624; -.
DR HOGENOM; CLU_090678_0_0_1; -.
DR InParanoid; Q9I8K7; -.
DR OrthoDB; 1378769at2759; -.
DR PhylomeDB; Q9I8K7; -.
DR TreeFam; TF331915; -.
DR Reactome; R-GGA-8866907; Activation of the TFAP2 (AP-2) family of transcription factors.
DR PRO; PR:Q9I8K7; -.
DR Proteomes; UP000000539; Chromosome 23.
DR Bgee; ENSGALG00000000678; Expressed in liver and 12 other tissues.
DR ExpressionAtlas; Q9I8K7; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR InterPro; IPR007576; CITED.
DR PANTHER; PTHR17045; PTHR17045; 1.
DR Pfam; PF04487; CITED; 1.
PE 2: Evidence at transcript level;
KW Activator; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..205
FT /note="Cbp/p300-interacting transactivator 3"
FT /id="PRO_0000409383"
SQ SEQUENCE 205 AA; 22335 MW; F97DC88D9F95FF9F CRC64;
MAEHMMMSMS HGGTGLQSYR MGVSGLQGPP QHGQHVLRTL PAAGQMMPYG GAGMDGAMRP
RPNLSGQMSH HQMQNAMMFN GPSQQQQQYM GPVGTQQLMA SMHLQKLNTQ YQGHPLGMSN
GPMGAGAQQY RVGPSQHPGM QHMPSPALTL NVMDTDLIDE EVLTSLVLEL GLDRIQELPE
LFLGQNEFDF ISDFVSKQQP SAISC