ID   CITG_VIBCH              Reviewed;         313 AA.
AC   Q9KTT7;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase;
DE            Short=2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase;
DE            EC=2.4.2.52;
GN   Name=citG; OrderedLocusNames=VC_0801;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3'-dephospho-CoA + ATP = 2'-(5''-triphospho-alpha-D-ribosyl)-
CC         3'-dephospho-CoA + adenine; Xref=Rhea:RHEA:15117, ChEBI:CHEBI:16708,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:57328, ChEBI:CHEBI:61378; EC=2.4.2.52;
CC   -!- SIMILARITY: Belongs to the CitG/MdcB family. {ECO:0000305}.
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DR   EMBL; AE003852; AAF93965.1; -; Genomic_DNA.
DR   PIR; C82278; C82278.
DR   RefSeq; NP_230450.1; NC_002505.1.
DR   RefSeq; WP_000154857.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KTT7; -.
DR   STRING; 243277.VC_0801; -.
DR   DNASU; 2615344; -.
DR   EnsemblBacteria; AAF93965; AAF93965; VC_0801.
DR   GeneID; 57739509; -.
DR   KEGG; vch:VC_0801; -.
DR   PATRIC; fig|243277.26.peg.764; -.
DR   eggNOG; COG1767; Bacteria.
DR   HOGENOM; CLU_056179_1_0_6; -.
DR   OMA; QSWQRPA; -.
DR   BioCyc; VCHO:VC0801-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046917; F:triphosphoribosyl-dephospho-CoA synthase activity; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:InterPro.
DR   GO; GO:0051191; P:prosthetic group biosynthetic process; IBA:GO_Central.
DR   HAMAP; MF_00397; CitG; 1.
DR   InterPro; IPR002736; CitG.
DR   InterPro; IPR017551; TriPribosyl-deP-CoA_syn_CitG.
DR   PANTHER; PTHR30201; PTHR30201; 1.
DR   Pfam; PF01874; CitG; 1.
DR   TIGRFAMs; TIGR03125; citrate_citG; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..313
FT                   /note="Probable 2-(5''-triphosphoribosyl)-3'-
FT                   dephosphocoenzyme-A synthase"
FT                   /id="PRO_0000214681"
SQ   SEQUENCE   313 AA;  33676 MW;  C2396934627F6148 CRC64;
     MTIPAALDLL LELPSQASSS SGSRTFSLPR LVGHLAYHAM MLEVHLTPKP GLVDTANNGA
     HRDMDLNTFI ASAEAIAPYL HSFVSAGWES AGNPAAQLLS ALRPIGIEAE QAMFAATQGV
     NTHKGMIFIL GLICGSVGWL KANQLKIDAQ HIGETIRQAC QFLVIDELKA KRDCEPETAG
     ERIYRQYGLT GARGEAASGL AMVMQHALPA YQACLTKGAS TEQALWHTLL VLMANNNDSN
     LVSRGGLAGL HFVQEQAQQL LAKGGFLYQE IEQALTALDS VLIEKHLSPG GSADLLAATW
     LIYELVQLFK VRH