ID   CITN_SALDU              Reviewed;         446 AA.
AC   P31603;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Citrate-sodium symporter;
DE   AltName: Full=Citrate carrier protein;
DE   AltName: Full=Citrate transporter;
GN   Name=citP; Synonyms=citC;
OS   Salmonella dublin.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=98360;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=35;
RX   PubMed=1374406; DOI=10.1016/s0021-9258(19)50127-2;
RA   Ishiguro N., Izawa H., Shinagawa M., Shimamoto T., Tsuchiya T.;
RT   "Cloning and nucleotide sequence of the gene (citC) encoding a citrate
RT   carrier from several Salmonella serovars.";
RL   J. Biol. Chem. 267:9559-9564(1992).
CC   -!- FUNCTION: Uptake of citrate across the boundary membrane with the
CC       concomitant uptake of a sodium ion (symport system).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the sodium:citrate (SCF) symporter family.
CC       {ECO:0000305}.
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DR   EMBL; D10258; BAA01100.1; -; Genomic_DNA.
DR   PIR; B42661; B42661.
DR   RefSeq; WP_000183596.1; NZ_VDCP01000009.1.
DR   AlphaFoldDB; P31603; -.
DR   SMR; P31603; -.
DR   PATRIC; fig|98360.39.peg.5154; -.
DR   OMA; NMGGTGD; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006101; P:citrate metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR018025; 2-OHcarbox_trans_Prot/Firm.
DR   InterPro; IPR004679; 2-OHcarboxylate_transport.
DR   PANTHER; PTHR40033; PTHR40033; 1.
DR   Pfam; PF03390; 2HCT; 1.
DR   PIRSF; PIRSF005348; YxkH; 1.
DR   TIGRFAMs; TIGR00783; ccs; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Citrate utilization; Membrane; Symport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..446
FT                   /note="Citrate-sodium symporter"
FT                   /id="PRO_0000088757"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        267..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        335..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        364..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   446 AA;  47592 MW;  902AAF356ADD9E06 CRC64;
     MTNMTQASAT EKKGAGDLLR FKIFGMPLPL YAFALITLLL SHFYNAIPTD LVGGFALMFV
     MGAIFGEIGK RLPIFNKYIG GAPVMIFLVA AYFVYAGIFT QKEIDAISNV MDKSNFLNLF
     IAVLITGAIL SVNRKLLLKS LLGYIPTILA GIVGASLFGI VIGLCFGIPV DRIMMLYVLP
     IMGGGNGAGA VPLSEIYHSV TGRSREEYYS TAIAILTIAN IFAIIFAALL DMIGKKYTWL
     SGEGELVRKA SFKTEDDEKA GQITHRETAV GMVLSTTCFL LAYVVAKKIL PSIGGVSIHY
     FAWMVLIVAA LNASGLCSPE IKAGAKRLSD FFSKQLLWVL MVGVGVCYTD LQEIIDALTF
     ANVVIAAIIV VGAVVGAAIG GWLIGFYPIE SSITAGLCMA NRGGSGDLEV LSACNRMNLI
     SYAQISSRLG GGIVLVIASI VFSMMV