CITT_ALKHC
ID CITT_ALKHC Reviewed; 230 AA.
AC Q9RC52;
DT 06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Transcriptional regulatory protein CitT;
GN Name=citT; OrderedLocusNames=BH3838;
OS Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS / JCM 9153 / C-125) (Bacillus halodurans).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX NCBI_TaxID=272558;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX PubMed=10484179; DOI=10.1007/s007920050120;
RA Takami H., Takaki Y., Nakasone K., Sakiyama T., Maeno G., Sasaki R.,
RA Hirama C., Fuji F., Masui N.;
RT "Genetic analysis of the chromosome of alkaliphilic Bacillus halodurans C-
RT 125.";
RL Extremophiles 3:227-233(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT and genomic sequence comparison with Bacillus subtilis.";
RL Nucleic Acids Res. 28:4317-4331(2000).
CC -!- FUNCTION: Member of the two-component regulatory system CitT/CitS.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- PTM: Phosphorylated by CitS. {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB024561; BAA83947.1; -; Genomic_DNA.
DR EMBL; BA000004; BAB07557.1; -; Genomic_DNA.
DR PIR; F84129; F84129.
DR RefSeq; WP_010899963.1; NC_002570.2.
DR AlphaFoldDB; Q9RC52; -.
DR SMR; Q9RC52; -.
DR STRING; 272558.10176463; -.
DR EnsemblBacteria; BAB07557; BAB07557; BAB07557.
DR KEGG; bha:BH3838; -.
DR eggNOG; COG4565; Bacteria.
DR HOGENOM; CLU_000445_39_0_9; -.
DR OMA; VGRPERC; -.
DR OrthoDB; 1755994at2; -.
DR Proteomes; UP000001258; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR024187; Sig_transdc_resp-reg_cit/mal.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR028141; Transcriptional_reg_dom.
DR PANTHER; PTHR45526; PTHR45526; 1.
DR Pfam; PF12431; CitT; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PIRSF; PIRSF006171; RR_citrat_malat; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Activator; Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome;
KW Transcription; Transcription regulation; Two-component regulatory system.
FT CHAIN 1..230
FT /note="Transcriptional regulatory protein CitT"
FT /id="PRO_0000081073"
FT DOMAIN 6..124
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DNA_BIND 184..203
FT /note="H-T-H motif"
FT /evidence="ECO:0000255"
FT MOD_RES 59
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 230 AA; 26482 MW; B85E130CC56C7663 CRC64;
MTKLYKVLII EDDFRVAQIQ EQMVNDHPYF HVISTCRTGG EALDYLSEKA AALDLILLDV
YIPDVKGLEL LWAIREKFRD VDIMMVTAAK EVDTVQEALR GGIIDYLLKP VQKEVLHQRL
DAYVQKRELF GERRQVSQEE LDQLRQVQVR VQVGETPLPK GIDRLTLEKV VNALEEAETQ
GLTAMEGARL IGASRSTVRR YFEYLIHTKK AKAEVNYGDV GRPERRYFLC
