ID   CK042_HUMAN             Reviewed;         333 AA.
AC   Q8N5U0;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-JUN-2006, sequence version 2.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Uncharacterized protein C11orf42;
GN   Name=C11orf42;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT SER-242.
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC031612; AAH31612.1; -; mRNA.
DR   CCDS; CCDS7759.1; -.
DR   RefSeq; NP_775796.2; NM_173525.2.
DR   AlphaFoldDB; Q8N5U0; -.
DR   BioGRID; 127751; 2.
DR   IntAct; Q8N5U0; 2.
DR   iPTMnet; Q8N5U0; -.
DR   PhosphoSitePlus; Q8N5U0; -.
DR   BioMuta; C11orf42; -.
DR   jPOST; Q8N5U0; -.
DR   MassIVE; Q8N5U0; -.
DR   PaxDb; Q8N5U0; -.
DR   PeptideAtlas; Q8N5U0; -.
DR   PRIDE; Q8N5U0; -.
DR   Antibodypedia; 57987; 20 antibodies from 11 providers.
DR   DNASU; 160298; -.
DR   Ensembl; ENST00000316375.3; ENSP00000321021.2; ENSG00000180878.3.
DR   GeneID; 160298; -.
DR   KEGG; hsa:160298; -.
DR   MANE-Select; ENST00000316375.3; ENSP00000321021.2; NM_173525.3; NP_775796.2.
DR   UCSC; uc001mcj.4; human.
DR   CTD; 160298; -.
DR   DisGeNET; 160298; -.
DR   GeneCards; C11orf42; -.
DR   HGNC; HGNC:28541; C11orf42.
DR   HPA; ENSG00000180878; Tissue enriched (testis).
DR   neXtProt; NX_Q8N5U0; -.
DR   OpenTargets; ENSG00000180878; -.
DR   PharmGKB; PA142672287; -.
DR   VEuPathDB; HostDB:ENSG00000180878; -.
DR   eggNOG; ENOG502S08J; Eukaryota.
DR   GeneTree; ENSGT00390000016268; -.
DR   HOGENOM; CLU_968206_0_0_1; -.
DR   InParanoid; Q8N5U0; -.
DR   OMA; FSCLKFA; -.
DR   OrthoDB; 1157936at2759; -.
DR   PhylomeDB; Q8N5U0; -.
DR   TreeFam; TF328634; -.
DR   PathwayCommons; Q8N5U0; -.
DR   SignaLink; Q8N5U0; -.
DR   BioGRID-ORCS; 160298; 5 hits in 1034 CRISPR screens.
DR   ChiTaRS; C11orf42; human.
DR   GenomeRNAi; 160298; -.
DR   Pharos; Q8N5U0; Tdark.
DR   PRO; PR:Q8N5U0; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   RNAct; Q8N5U0; protein.
DR   Bgee; ENSG00000180878; Expressed in left testis and 88 other tissues.
DR   Genevisible; Q8N5U0; HS.
DR   InterPro; IPR031366; DUF4663.
DR   PANTHER; PTHR36872; PTHR36872; 1.
DR   Pfam; PF15668; DUF4663; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..333
FT                   /note="Uncharacterized protein C11orf42"
FT                   /id="PRO_0000240702"
FT   REGION          234..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        249..268
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         242
FT                   /note="P -> S (in dbSNP:rs10769671)"
FT                   /evidence="ECO:0000269|PubMed:15489334"
FT                   /id="VAR_026831"
SQ   SEQUENCE   333 AA;  36368 MW;  2402D0C7C8F14996 CRC64;
     MLVGTPNLLT LDEADATWTL IKDKVIEEHF GPNAVAVPFL SDAACYDLLG VLVKQSRPAH
     TRLALPGRQG RRALKPVGPL PSLLEQAGSE GAFAHCTREY SPNGRAERAY EETRMLDGQP
     CKIRLHMGDL RKKVAFLLLP PGQVSLQQTL PWLRSTHSIY VIYQVFSCSW LQLGLTSTAR
     EPQLLRLLRS LPVAFSCLKF SLQSKGVLGP QKPLTKDPLP HGANWVRPNL SIMPPLAPTS
     APADTTEAAD VPPPVPAPPT PPPQEGPEDK PTRFSYKGRN PFWRGPQILS ENWLFSPRSP
     PPGAQGGGPR DPDGHSMSLP LLQGLSSEFD SDD