CK052_MOUSE
ID CK052_MOUSE Reviewed; 127 AA.
AC Q9D8L0; Q9CPS4;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Uncharacterized protein C11orf52 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Pancreas, and Tongue;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=C57BL/6J, and FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9D8L0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9D8L0-2; Sequence=VSP_021875;
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DR EMBL; AK007611; BAB25134.1; -; mRNA.
DR EMBL; AK007929; BAB25356.1; -; mRNA.
DR EMBL; AK009541; BAB26348.1; -; mRNA.
DR EMBL; BC027409; AAH27409.1; -; mRNA.
DR CCDS; CCDS23170.1; -. [Q9D8L0-1]
DR RefSeq; NP_080141.1; NM_025865.2. [Q9D8L0-1]
DR AlphaFoldDB; Q9D8L0; -.
DR STRING; 10090.ENSMUSP00000034564; -.
DR iPTMnet; Q9D8L0; -.
DR PhosphoSitePlus; Q9D8L0; -.
DR MaxQB; Q9D8L0; -.
DR PaxDb; Q9D8L0; -.
DR PRIDE; Q9D8L0; -.
DR Antibodypedia; 51501; 24 antibodies from 10 providers.
DR DNASU; 66952; -.
DR Ensembl; ENSMUST00000034564; ENSMUSP00000034564; ENSMUSG00000032062. [Q9D8L0-1]
DR Ensembl; ENSMUST00000239417; ENSMUSP00000159377; ENSMUSG00000032062. [Q9D8L0-2]
DR GeneID; 66952; -.
DR KEGG; mmu:66952; -.
DR UCSC; uc009pki.1; mouse. [Q9D8L0-2]
DR MGI; MGI:1914202; 2310030G06Rik.
DR VEuPathDB; HostDB:ENSMUSG00000032062; -.
DR eggNOG; ENOG502S7WW; Eukaryota.
DR GeneTree; ENSGT00390000015195; -.
DR HOGENOM; CLU_1980817_0_0_1; -.
DR InParanoid; Q9D8L0; -.
DR OMA; ESNLHYA; -.
DR OrthoDB; 1424932at2759; -.
DR PhylomeDB; Q9D8L0; -.
DR TreeFam; TF336887; -.
DR BioGRID-ORCS; 66952; 2 hits in 71 CRISPR screens.
DR PRO; PR:Q9D8L0; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q9D8L0; protein.
DR Bgee; ENSMUSG00000032062; Expressed in ectoplacental cone and 187 other tissues.
DR Genevisible; Q9D8L0; MM.
DR InterPro; IPR028106; DUF4578.
DR PANTHER; PTHR37342; PTHR37342; 1.
DR Pfam; PF15147; DUF4578; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Phosphoprotein; Reference proteome.
FT CHAIN 1..127
FT /note="Uncharacterized protein C11orf52 homolog"
FT /id="PRO_0000263610"
FT REGION 51..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 30
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q96A22"
FT MOD_RES 63
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96A22"
FT VAR_SEQ 1
FT /note="M -> MSENQLGSLGDTTAM (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334,
FT ECO:0000303|PubMed:16141072"
FT /id="VSP_021875"
SQ SEQUENCE 127 AA; 14283 MW; C4CEB04B162CD354 CRC64;
MGNRLCCGGT WSCPSTFQKK SKTGSHPRPT LSILKQQQLW QNGTKDYETT APTYEQVLYP
PASQKKTSNS TSEESDLHYA DIHVLRQIRP HSLHTVKCLH SESATEYATL RFPQATPQYD
SNNGTLV
