CK054_BOVIN
ID CK054_BOVIN Reviewed; 315 AA.
AC Q2HJH3;
DT 11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Ester hydrolase C11orf54 homolog;
DE EC=3.1.-.-;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Exhibits ester hydrolase activity on the substrate p-
CC nitrophenyl acetate. {ECO:0000250}.
CC -!- SUBUNIT: Monomer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR EMBL; BC105390; AAI05391.1; -; mRNA.
DR RefSeq; NP_001039780.1; NM_001046315.2.
DR RefSeq; XP_005226700.1; XM_005226643.3.
DR RefSeq; XP_005226701.1; XM_005226644.3.
DR AlphaFoldDB; Q2HJH3; -.
DR SMR; Q2HJH3; -.
DR STRING; 9913.ENSBTAP00000004617; -.
DR PaxDb; Q2HJH3; -.
DR PeptideAtlas; Q2HJH3; -.
DR PRIDE; Q2HJH3; -.
DR Ensembl; ENSBTAT00000004617; ENSBTAP00000004617; ENSBTAG00000003550.
DR GeneID; 530784; -.
DR KEGG; bta:530784; -.
DR CTD; 530784; -.
DR VEuPathDB; HostDB:ENSBTAG00000003550; -.
DR VGNC; VGNC:52699; C29H11orf54.
DR eggNOG; KOG4048; Eukaryota.
DR GeneTree; ENSGT00390000017214; -.
DR HOGENOM; CLU_055541_0_0_1; -.
DR InParanoid; Q2HJH3; -.
DR OMA; HIMPDFS; -.
DR OrthoDB; 877242at2759; -.
DR TreeFam; TF313169; -.
DR Proteomes; UP000009136; Chromosome 29.
DR Bgee; ENSBTAG00000003550; Expressed in liver and 104 other tissues.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR InterPro; IPR015021; DUF1907.
DR PANTHER; PTHR13204; PTHR13204; 1.
DR Pfam; PF08925; DUF1907; 1.
DR SMART; SM01168; DUF1907; 1.
PE 2: Evidence at transcript level;
KW Hydrolase; Metal-binding; Nucleus; Reference proteome; Zinc.
FT CHAIN 1..315
FT /note="Ester hydrolase C11orf54 homolog"
FT /id="PRO_0000246028"
FT BINDING 266
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
FT BINDING 268
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
FT BINDING 278
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
SQ SEQUENCE 315 AA; 35155 MW; DEE5BAE59A344BE1 CRC64;
MACAEYSFHV PSLEELVGVL QKGLTDNFAE VQVSVVDCPD LTKEPFTFPI KGICGKTRIA
EVGGVPYLLP LVNEKKVYDL NKIAKDIQLP GAFVLGAGAG PFQTLGFNSE FMLLVQTESE
HRPPVNGSYF ARVNPADGGC LLEKYSEKYH DFGCALLANL FASEGQPGKV IEVKVKRRTG
KLNFVTCMRQ TLEKHYGDKP VGMGGAFIIQ KGKVKTHIMP AEFSSCPLNS DEDVNKWLHF
YEMKAPLVCL PVFVSRDPGF DLRLEHTHCF SHHGEGGHYH YDTTPDIVEY LGYFLPAEFL
YRIDQPKETH SFGRD