ID   CK054_DANRE             Reviewed;         319 AA.
AC   Q6NWE0; Q6PHI5;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Ester hydrolase C11orf54 homolog;
DE            EC=3.1.-.-;
GN   ORFNames=zgc:85789;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits ester hydrolase activity on the substrate p-
CC       nitrophenyl acetate. {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC056539; AAH56539.1; -; mRNA.
DR   EMBL; BC067627; AAH67627.1; -; mRNA.
DR   RefSeq; NP_997781.1; NM_212616.1.
DR   AlphaFoldDB; Q6NWE0; -.
DR   SMR; Q6NWE0; -.
DR   STRING; 7955.ENSDARP00000038075; -.
DR   PaxDb; Q6NWE0; -.
DR   Ensembl; ENSDART00000180089; ENSDARP00000148836; ENSDARG00000110147.
DR   GeneID; 322350; -.
DR   KEGG; dre:322350; -.
DR   ZFIN; ZDB-GENE-030131-1069; zgc:85789.
DR   eggNOG; KOG4048; Eukaryota.
DR   GeneTree; ENSGT00390000017214; -.
DR   HOGENOM; CLU_055541_0_0_1; -.
DR   InParanoid; Q6NWE0; -.
DR   OMA; HIMPDFS; -.
DR   OrthoDB; 877242at2759; -.
DR   PhylomeDB; Q6NWE0; -.
DR   PRO; PR:Q6NWE0; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 5.
DR   Bgee; ENSDARG00000110147; Expressed in liver and 32 other tissues.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR   InterPro; IPR015021; DUF1907.
DR   PANTHER; PTHR13204; PTHR13204; 1.
DR   Pfam; PF08925; DUF1907; 1.
DR   SMART; SM01168; DUF1907; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Metal-binding; Nucleus; Reference proteome; Zinc.
FT   CHAIN           1..319
FT                   /note="Ester hydrolase C11orf54 homolog"
FT                   /id="PRO_0000246032"
FT   BINDING         270
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         272
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         282
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   319 AA;  35238 MW;  D95602BBD2695893 CRC64;
     MDNSGKTEKF QLHVPNLEEL CQVLESGLNK NFSDVKVSVT DCPDLTQQPF GFPVKGLCGK
     PRITDVGGVP NLIPLVKLDK VYNMNSVSKE VELPGAFILG AGAISFKTAG INGELMPLVL
     TEAEGRSAVN ASYFSSINPE DGKCLQEKYS DRFDDCDFGL LANLYACEGK PGKVIEVKAC
     RRTGEDSLVS CMRKTMAEHY GEKSVALGGT FIIQKGKAKI HIMPREFSVC PLNTDEDVNN
     WLRHFEVSAP LIFQTVMISR DPGLDLRVEH THGFSHHGEG GHYYTDTTPN TVEYLGYFLP
     AETVYRIDRP TETHNVGRD