ID   CK054_XENLA             Reviewed;         316 AA.
AC   Q6GME2;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Ester hydrolase C11orf54 homolog;
DE            EC=3.1.-.-;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits ester hydrolase activity on the substrate p-
CC       nitrophenyl acetate. {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC074124; AAH74124.1; -; mRNA.
DR   RefSeq; NP_001086047.1; NM_001092578.1.
DR   AlphaFoldDB; Q6GME2; -.
DR   SMR; Q6GME2; -.
DR   MaxQB; Q6GME2; -.
DR   DNASU; 444476; -.
DR   GeneID; 444476; -.
DR   KEGG; xla:444476; -.
DR   CTD; 444476; -.
DR   Xenbase; XB-GENE-1010640; c11orf54.L.
DR   OMA; HIMPDFS; -.
DR   OrthoDB; 877242at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 444476; Expressed in kidney and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR015021; DUF1907.
DR   PANTHER; PTHR13204; PTHR13204; 1.
DR   Pfam; PF08925; DUF1907; 1.
DR   SMART; SM01168; DUF1907; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Metal-binding; Nucleus; Reference proteome; Zinc.
FT   CHAIN           1..316
FT                   /note="Ester hydrolase C11orf54 homolog"
FT                   /id="PRO_0000246033"
FT   BINDING         267
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         269
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         279
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   316 AA;  34908 MW;  F2FF974395488497 CRC64;
     MAETESCTFH VPSLEEICSI LKSGLLKNFA DVNVIVTECP DLTKEPFEFP VKGLCGKSRI
     ADVGGVPYLV PMPRLDKVYN VNTVAKKIGL PGAYILGAGA TSHRSLGMNA ELIFSVQAES
     TSTLAVNKSY VASVNPGDGS CLLEKYRDRN NDNDFGLLSN LYACEGKPGK VIEVSVKRRI
     GQDNFVSCMR KSLKEHYGEN AVGMGGTFLI KQGKAKLHVM PREYSACPLN TDEDVNGWLK
     FYDMTAPLIC QSVFVSHDPG YDLRLEHTHC YSHHGEGGHY HYDTTPDTVE YLGYFHPAEF
     LYRIDKPSAT HLVGRD