CK086_HUMAN
ID CK086_HUMAN Reviewed; 115 AA.
AC A6NJI1;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 2.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Uncharacterized protein C11orf86;
GN Name=C11orf86;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Small intestine;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
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DR EMBL; AK026328; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AP003176; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS44656.1; -.
DR RefSeq; NP_001129957.1; NM_001136485.1.
DR AlphaFoldDB; A6NJI1; -.
DR STRING; 9606.ENSP00000311479; -.
DR iPTMnet; A6NJI1; -.
DR PhosphoSitePlus; A6NJI1; -.
DR BioMuta; C11orf86; -.
DR MassIVE; A6NJI1; -.
DR MaxQB; A6NJI1; -.
DR PaxDb; A6NJI1; -.
DR PeptideAtlas; A6NJI1; -.
DR PRIDE; A6NJI1; -.
DR Antibodypedia; 52590; 7 antibodies from 6 providers.
DR DNASU; 254439; -.
DR Ensembl; ENST00000308963.4; ENSP00000311479.4; ENSG00000173237.5.
DR GeneID; 254439; -.
DR KEGG; hsa:254439; -.
DR UCSC; uc010rpm.3; human.
DR CTD; 254439; -.
DR GeneCards; C11orf86; -.
DR HGNC; HGNC:34442; C11orf86.
DR HPA; ENSG00000173237; Tissue enriched (intestine).
DR neXtProt; NX_A6NJI1; -.
DR OpenTargets; ENSG00000173237; -.
DR PharmGKB; PA162377813; -.
DR VEuPathDB; HostDB:ENSG00000173237; -.
DR eggNOG; ENOG502SY9F; Eukaryota.
DR GeneTree; ENSGT00390000012120; -.
DR HOGENOM; CLU_164853_0_0_1; -.
DR InParanoid; A6NJI1; -.
DR OMA; WERFVAI; -.
DR OrthoDB; 1606615at2759; -.
DR PhylomeDB; A6NJI1; -.
DR TreeFam; TF336876; -.
DR PathwayCommons; A6NJI1; -.
DR SignaLink; A6NJI1; -.
DR BioGRID-ORCS; 254439; 7 hits in 1033 CRISPR screens.
DR GenomeRNAi; 254439; -.
DR Pharos; A6NJI1; Tdark.
DR PRO; PR:A6NJI1; -.
DR Proteomes; UP000005640; Chromosome 11.
DR RNAct; A6NJI1; protein.
DR Bgee; ENSG00000173237; Expressed in ileal mucosa and 46 other tissues.
DR Genevisible; A6NJI1; HS.
DR InterPro; IPR027990; DUF4633.
DR PANTHER; PTHR31831; PTHR31831; 1.
DR Pfam; PF15464; DUF4633; 1.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..115
FT /note="Uncharacterized protein C11orf86"
FT /id="PRO_0000328809"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 115 AA; 13172 MW; 53E732FEFCF13C1B CRC64;
MGTGLRSQSL REPRPSYGKL QEPWGRPQEG QLRRALSLRQ GQEKSRSQGL ERGTEGPDAT
AQERVPGSLG DTEQLIQAQR RGSRWWLRRY QQVRRRWESF VAIFPSVTLS QPASP