CK087_MOUSE
ID CK087_MOUSE Reviewed; 199 AA.
AC Q32M26; Q8CC42;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Uncharacterized protein C11orf87 homolog;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Diencephalon;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC28535.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AK033979; BAC28535.1; ALT_FRAME; mRNA.
DR EMBL; BC109328; AAI09329.1; -; mRNA.
DR CCDS; CCDS52795.1; -.
DR RefSeq; NP_001273570.1; NM_001286641.1.
DR RefSeq; NP_849237.2; NM_178906.5.
DR RefSeq; XP_006510521.1; XM_006510458.3.
DR RefSeq; XP_011240867.1; XM_011242565.2.
DR AlphaFoldDB; Q32M26; -.
DR SMR; Q32M26; -.
DR STRING; 10090.ENSMUSP00000096365; -.
DR GlyConnect; 2812; 2 N-Linked glycans (2 sites).
DR GlyGen; Q32M26; 2 sites, 2 N-linked glycans (2 sites).
DR PhosphoSitePlus; Q32M26; -.
DR MaxQB; Q32M26; -.
DR PaxDb; Q32M26; -.
DR PeptideAtlas; Q32M26; -.
DR PRIDE; Q32M26; -.
DR Antibodypedia; 32002; 25 antibodies from 14 providers.
DR DNASU; 330941; -.
DR Ensembl; ENSMUST00000098768; ENSMUSP00000096365; ENSMUSG00000078307.
DR Ensembl; ENSMUST00000213937; ENSMUSP00000149532; ENSMUSG00000078307.
DR GeneID; 330941; -.
DR KEGG; mmu:330941; -.
DR UCSC; uc009plx.3; mouse.
DR MGI; MGI:2143099; AI593442.
DR VEuPathDB; HostDB:ENSMUSG00000078307; -.
DR eggNOG; ENOG502S981; Eukaryota.
DR GeneTree; ENSGT00390000012905; -.
DR HOGENOM; CLU_074982_0_0_1; -.
DR InParanoid; Q32M26; -.
DR OMA; HIHKRKM; -.
DR OrthoDB; 1553910at2759; -.
DR PhylomeDB; Q32M26; -.
DR TreeFam; TF336990; -.
DR BioGRID-ORCS; 330941; 4 hits in 71 CRISPR screens.
DR PRO; PR:Q32M26; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q32M26; protein.
DR Bgee; ENSMUSG00000078307; Expressed in caudate-putamen and 107 other tissues.
DR ExpressionAtlas; Q32M26; baseline and differential.
DR Genevisible; Q32M26; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR037670; C11orf87.
DR PANTHER; PTHR31870; PTHR31870; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..199
FT /note="Uncharacterized protein C11orf87 homolog"
FT /id="PRO_0000320197"
FT TOPO_DOM 24..60
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 82..199
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 93..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..176
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 19
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 26
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 105..106
FT /note="CS -> WT (in Ref. 1; BAC28535)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 199 AA; 20718 MW; C48D626495315BB4 CRC64;
MSARAPKELR LALPPCLLNR TFASHNASGG SSAGLRSSGA GGGTCITQVG QQLFQSFSST
LVLIVLVTLI FCLLVLSLST FHIHKRRMKK RKMQRAQEEY ERDHCSGSHG GGGLPRAGVQ
APTHGKETRL ERQPRDSAFC TPSNATSSSS SSSSSPGLLC QGPCAPPPPL PAPTPQGAPA
ASSCLDTPGE GLLQTVVLS
