ID   CK091_HUMAN             Reviewed;         193 AA.
AC   Q3C1V1; Q3C1V2;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Uncharacterized protein C11orf91;
GN   Name=C11orf91;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 119-185 (ISOFORM 1), AND
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 116-193 (ISOFORM 2).
RA   Totoki Y., Yada T., Sakaki Y., Takeda T.;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q3C1V1-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q3C1V1-2; Sequence=VSP_034218;
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DR   EMBL; AL049629; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AB231759; BAE46895.1; -; mRNA.
DR   EMBL; AB231760; BAE46896.1; -; mRNA.
DR   CCDS; CCDS53615.1; -. [Q3C1V1-1]
DR   RefSeq; NP_001160164.1; NM_001166692.1. [Q3C1V1-1]
DR   RefSeq; XP_016872542.1; XM_017017053.1. [Q3C1V1-1]
DR   AlphaFoldDB; Q3C1V1; -.
DR   BioGRID; 935242; 1.
DR   STRING; 9606.ENSP00000368296; -.
DR   iPTMnet; Q3C1V1; -.
DR   PhosphoSitePlus; Q3C1V1; -.
DR   BioMuta; C11orf91; -.
DR   DMDM; 190461789; -.
DR   MassIVE; Q3C1V1; -.
DR   PaxDb; Q3C1V1; -.
DR   PeptideAtlas; Q3C1V1; -.
DR   PRIDE; Q3C1V1; -.
DR   ProteomicsDB; 61682; -. [Q3C1V1-1]
DR   ProteomicsDB; 61683; -. [Q3C1V1-2]
DR   Antibodypedia; 62997; 22 antibodies from 9 providers.
DR   DNASU; 100131378; -.
DR   Ensembl; ENST00000379011.5; ENSP00000368296.4; ENSG00000205177.7. [Q3C1V1-1]
DR   GeneID; 100131378; -.
DR   KEGG; hsa:100131378; -.
DR   MANE-Select; ENST00000379011.5; ENSP00000368296.4; NM_001166692.2; NP_001160164.1.
DR   UCSC; uc001mur.3; human. [Q3C1V1-1]
DR   CTD; 100131378; -.
DR   GeneCards; C11orf91; -.
DR   HGNC; HGNC:34444; C11orf91.
DR   HPA; ENSG00000205177; Tissue enhanced (adipose tissue, testis).
DR   neXtProt; NX_Q3C1V1; -.
DR   OpenTargets; ENSG00000205177; -.
DR   PharmGKB; PA164716759; -.
DR   VEuPathDB; HostDB:ENSG00000205177; -.
DR   eggNOG; ENOG502S5Z2; Eukaryota.
DR   GeneTree; ENSGT00390000002169; -.
DR   HOGENOM; CLU_1402030_0_0_1; -.
DR   InParanoid; Q3C1V1; -.
DR   OMA; KMSQRPA; -.
DR   OrthoDB; 1606594at2759; -.
DR   PhylomeDB; Q3C1V1; -.
DR   TreeFam; TF339799; -.
DR   PathwayCommons; Q3C1V1; -.
DR   BioGRID-ORCS; 100131378; 14 hits in 1038 CRISPR screens.
DR   Pharos; Q3C1V1; Tdark.
DR   PRO; PR:Q3C1V1; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   RNAct; Q3C1V1; protein.
DR   Bgee; ENSG00000205177; Expressed in lower esophagus mucosa and 87 other tissues.
DR   ExpressionAtlas; Q3C1V1; baseline and differential.
DR   InterPro; IPR040027; C11orf91-like.
DR   PANTHER; PTHR36288; PTHR36288; 1.
DR   Pfam; PF17669; DUF5529; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..193
FT                   /note="Uncharacterized protein C11orf91"
FT                   /id="PRO_0000340697"
FT   REGION          55..94
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        69..94
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         166..193
FT                   /note="YTFLKALKDEKLQGLKTKQPGKKSASLS -> FLGLWTTCADAGRIPQPTS
FT                   (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.2"
FT                   /id="VSP_034218"
FT   CONFLICT        119
FT                   /note="V -> F (in Ref. 2; BAE46895)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        147
FT                   /note="R -> L (in Ref. 2; BAE46895)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        149
FT                   /note="K -> Q (in Ref. 2; BAE46895)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   193 AA;  20547 MW;  6589D2D6F07EDA2E CRC64;
     MPKGRRGSHS PTMSQRSAPP LYFPSLYDRG ISSSPLSDFN IWKKLFVPLK AGGAPVGGAA
     GARSLSQALP APAPPPPPPP GLGPSSERPW PSPWPSGLAS IPYEPLRFFY SPPPGPEVVA
     SPLVPCPSTP RLASASHPEE LCELEIRIKE LELLTITGDG FDSQSYTFLK ALKDEKLQGL
     KTKQPGKKSA SLS