CK094_HUMAN
ID CK094_HUMAN Reviewed; 98 AA.
AC C9JXX5;
DT 18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT 03-NOV-2009, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Uncharacterized protein C11orf94;
DE Flags: Precursor;
GN Name=C11orf94;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR EMBL; AC068385; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471064; EAW68025.1; -; Genomic_DNA.
DR CCDS; CCDS44577.1; -.
DR RefSeq; NP_001073915.2; NM_001080446.2.
DR AlphaFoldDB; C9JXX5; -.
DR STRING; 9606.ENSP00000401498; -.
DR iPTMnet; C9JXX5; -.
DR PhosphoSitePlus; C9JXX5; -.
DR BioMuta; C11orf94; -.
DR PaxDb; C9JXX5; -.
DR PeptideAtlas; C9JXX5; -.
DR PRIDE; C9JXX5; -.
DR Antibodypedia; 71796; 8 antibodies from 7 providers.
DR DNASU; 143678; -.
DR Ensembl; ENST00000449465.2; ENSP00000401498.1; ENSG00000234776.5.
DR GeneID; 143678; -.
DR KEGG; hsa:143678; -.
DR MANE-Select; ENST00000449465.2; ENSP00000401498.1; NM_001080446.3; NP_001073915.2.
DR UCSC; uc001nbs.5; human.
DR CTD; 143678; -.
DR GeneCards; C11orf94; -.
DR HGNC; HGNC:37213; C11orf94.
DR HPA; ENSG00000234776; Tissue enriched (testis).
DR neXtProt; NX_C9JXX5; -.
DR OpenTargets; ENSG00000234776; -.
DR PharmGKB; PA165543255; -.
DR VEuPathDB; HostDB:ENSG00000234776; -.
DR eggNOG; ENOG502SCAR; Eukaryota.
DR GeneTree; ENSGT00390000018235; -.
DR HOGENOM; CLU_2319619_0_0_1; -.
DR InParanoid; C9JXX5; -.
DR OMA; MADYYYD; -.
DR OrthoDB; 1586293at2759; -.
DR PhylomeDB; C9JXX5; -.
DR TreeFam; TF339805; -.
DR PathwayCommons; C9JXX5; -.
DR BioGRID-ORCS; 143678; 8 hits in 1047 CRISPR screens.
DR GenomeRNAi; 143678; -.
DR Pharos; C9JXX5; Tdark.
DR PRO; PR:C9JXX5; -.
DR Proteomes; UP000005640; Chromosome 11.
DR RNAct; C9JXX5; protein.
DR Bgee; ENSG00000234776; Expressed in left testis and 97 other tissues.
DR Genevisible; C9JXX5; HS.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR031748; DUF4733.
DR PANTHER; PTHR37872; PTHR37872; 1.
DR Pfam; PF15878; DUF4733; 1.
PE 3: Inferred from homology;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..30
FT /evidence="ECO:0000255"
FT CHAIN 31..98
FT /note="Uncharacterized protein C11orf94"
FT /id="PRO_0000394235"
FT REGION 60..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 80
FT /note="Q -> H (in dbSNP:rs2271849)"
FT /id="VAR_063154"
SQ SEQUENCE 98 AA; 10902 MW; CBBEF44FF40AEFA2 CRC64;
MVLAMLGALH PRAGLSLFLH LILAVALLRS QPLRSQRSVP EAFSAPLELS QPLSGLVDDY
GILPKHPRPR GPRPLLSRAQ QRKRDGPDLA EYYYDAHL