CK096_RAT
ID CK096_RAT Reviewed; 242 AA.
AC A8IHN8;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 1.
DT 03-AUG-2022, entry version 52.
DE RecName: Full=Uncharacterized protein C11orf96 homolog;
DE AltName: Full=Protein Ag2;
GN Name=Ag2;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Wistar; TISSUE=Hippocampus;
RA Inokuchi K.;
RT "Ag2, a gene upregulated during hippocampal long-term potentiation.";
RL Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP INDUCTION.
RX PubMed=10820183; DOI=10.1046/j.1471-4159.2000.0742239.x;
RA Matsuo R., Murayama A., Saitoh Y., Sakaki Y., Inokuchi K.;
RT "Identification and cataloging of genes induced by long-lasting long-term
RT potentiation in awake rats.";
RL J. Neurochem. 74:2239-2249(2000).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-192; SER-206; SER-232 AND
RP SER-238, AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22673903; DOI=10.1038/ncomms1871;
RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA Olsen J.V.;
RT "Quantitative maps of protein phosphorylation sites across 14 different rat
RT organs and tissues.";
RL Nat. Commun. 3:876-876(2012).
CC -!- INDUCTION: Expression in the hippocampus is induced by long-lasting
CC long-term potentiation. {ECO:0000269|PubMed:10820183}.
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DR EMBL; AB010079; BAF81982.1; -; mRNA.
DR RefSeq; NP_001103525.1; NM_001110055.1.
DR AlphaFoldDB; A8IHN8; -.
DR SMR; A8IHN8; -.
DR iPTMnet; A8IHN8; -.
DR PhosphoSitePlus; A8IHN8; -.
DR PeptideAtlas; A8IHN8; -.
DR PRIDE; A8IHN8; -.
DR Ensembl; ENSRNOT00000088555; ENSRNOP00000072215; ENSRNOG00000055564.
DR GeneID; 499839; -.
DR KEGG; rno:499839; -.
DR UCSC; RGD:1564664; rat.
DR CTD; 499839; -.
DR RGD; 1564664; RGD1564664.
DR GeneTree; ENSGT00390000016821; -.
DR HOGENOM; CLU_1245012_0_0_1; -.
DR InParanoid; A8IHN8; -.
DR OMA; RRHPTAD; -.
DR OrthoDB; 1458889at2759; -.
DR PhylomeDB; A8IHN8; -.
DR PRO; PR:A8IHN8; -.
DR Proteomes; UP000002494; Chromosome 3.
DR Bgee; ENSRNOG00000055564; Expressed in stomach and 19 other tissues.
DR Genevisible; A8IHN8; RN.
DR InterPro; IPR031521; DUF4695.
DR PANTHER; PTHR40250; PTHR40250; 1.
DR Pfam; PF15766; DUF4695; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..242
FT /note="Uncharacterized protein C11orf96 homolog"
FT /id="PRO_0000320643"
FT REGION 16..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..112
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 175
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q7Z7L8"
FT MOD_RES 192
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:22673903"
FT MOD_RES 206
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:22673903"
FT MOD_RES 216
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q3UPL5"
FT MOD_RES 232
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:22673903"
FT MOD_RES 238
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:22673903"
SQ SEQUENCE 242 AA; 26097 MW; 8418B039CDFC42B1 CRC64;
MAFAVIRACS RVGRGGLYKR LGGLPRGTRR QRQRRQGASL STTEQRSLAP RPPTGPPARY
PSPAVPARAS EARRHPAADL DPPPGEPQAV ASRGTPEPRP PPESPGAQPP PGPAAADGAM
AAAKPGELMG ISSSYQAVMP HFVCLADEFP QPVRPAKLPK GKGRLRRPRQ SRFKTQPVTF
DEIQEVEEEG VSPMEEEKAK KSFLQSLECL RRSTQSLSLQ REPLGSCKLR NSLDSSDSDS
AL