ID   CK2N2_XENLA             Reviewed;          79 AA.
AC   Q6P6Z4;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase II inhibitor 2;
GN   Name=camk2n2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Potent and specific cellular inhibitor of CaM-kinase II
CC       (CAMK2). Traps Ca(2+)/calmodulin on CAMK2 (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytosol
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CAMK2N family. {ECO:0000305}.
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DR   EMBL; BC061942; AAH61942.1; -; mRNA.
DR   RefSeq; NP_001165246.1; NM_001171775.1.
DR   AlphaFoldDB; Q6P6Z4; -.
DR   DNASU; 779109; -.
DR   GeneID; 779109; -.
DR   KEGG; xla:779109; -.
DR   CTD; 779109; -.
DR   OrthoDB; 1637105at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 779109; Expressed in neurula embryo and 13 other tissues.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR026779; Camk2n.
DR   PANTHER; PTHR31007; PTHR31007; 1.
DR   Pfam; PF15170; CaM-KIIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Protein kinase inhibitor; Reference proteome.
FT   CHAIN           1..79
FT                   /note="Calcium/calmodulin-dependent protein kinase II
FT                   inhibitor 2"
FT                   /id="PRO_0000327269"
FT   REGION          43..69
FT                   /note="Inhibitory domain"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   79 AA;  8660 MW;  0F57CAE86FE750C2 CRC64;
     MSEILPYSDE KMGHYGSDGE VGQISFSCRL QDTSSFFGGN QQKRPPKLGQ IGRAKRVVIE
     DDRIDEVLKG VSDKSPSGV