ID   CKS2_XENLA              Reviewed;          79 AA.
AC   Q91879; Q5D029;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Cyclin-dependent kinases regulatory subunit 2;
DE   AltName: Full=Xe-p9;
GN   Name=cks2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8666234; DOI=10.1101/gad.10.12.1503;
RA   Patra D., Dunphy W.G.;
RT   "Xe-p9, a Xenopus Suc1/Cks homolog, has multiple essential roles in cell
RT   cycle control.";
RL   Genes Dev. 10:1503-1515(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds to the catalytic subunit of the cyclin dependent
CC       kinases and is essential for their biological function.
CC   -!- SUBUNIT: Forms a homohexamer that can probably bind six kinase
CC       subunits. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CKS family. {ECO:0000305}.
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DR   EMBL; U56426; AAC59914.1; -; mRNA.
DR   EMBL; BC068722; AAH68722.1; -; mRNA.
DR   RefSeq; NP_001081798.1; NM_001088329.1.
DR   AlphaFoldDB; Q91879; -.
DR   SMR; Q91879; -.
DR   DNASU; 398059; -.
DR   GeneID; 398059; -.
DR   KEGG; xla:398059; -.
DR   CTD; 398059; -.
DR   Xenbase; XB-GENE-17345494; cks2.S.
DR   OMA; CIQNCER; -.
DR   OrthoDB; 1377855at2759; -.
DR   Proteomes; UP000186698; Chromosome 1S.
DR   Bgee; 398059; Expressed in egg cell and 17 other tissues.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.170.10; -; 1.
DR   InterPro; IPR000789; Cyclin-dep_kinase_reg-sub.
DR   InterPro; IPR036858; Cyclin-dep_kinase_reg-sub_sf.
DR   Pfam; PF01111; CKS; 1.
DR   PRINTS; PR00296; CYCLINKINASE.
DR   SMART; SM01084; CKS; 1.
DR   SUPFAM; SSF55637; SSF55637; 1.
DR   PROSITE; PS00944; CKS_1; 1.
DR   PROSITE; PS00945; CKS_2; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Reference proteome.
FT   CHAIN           1..79
FT                   /note="Cyclin-dependent kinases regulatory subunit 2"
FT                   /id="PRO_0000206239"
SQ   SEQUENCE   79 AA;  9782 MW;  26135574BF0494F9 CRC64;
     MSYKNIYYSD KYTDEHFEYR HVMLPKELAK QVPKTHLMSE EEWRRLGVQQ SLGWVHYMIH
     EPEPHILLFR RPLPKDQQK