ID   CL004_PONAB             Reviewed;         552 AA.
AC   Q5RD58;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Protein C12orf4 homolog;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in mast cell degranulation.
CC       {ECO:0000250|UniProtKB:D4A770}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:D4A770}.
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DR   EMBL; CR858060; CAH90299.1; -; mRNA.
DR   RefSeq; NP_001125138.1; NM_001131666.1.
DR   RefSeq; XP_009245610.1; XM_009247335.1.
DR   AlphaFoldDB; Q5RD58; -.
DR   SMR; Q5RD58; -.
DR   STRING; 9601.ENSPPYP00000004748; -.
DR   Ensembl; ENSPPYT00000004936; ENSPPYP00000004748; ENSPPYG00000004167.
DR   GeneID; 100172023; -.
DR   KEGG; pon:100172023; -.
DR   CTD; 113584989; -.
DR   eggNOG; KOG4506; Eukaryota.
DR   GeneTree; ENSGT00390000010229; -.
DR   HOGENOM; CLU_036084_0_0_1; -.
DR   InParanoid; Q5RD58; -.
DR   OMA; EMASWGG; -.
DR   OrthoDB; 743423at2759; -.
DR   TreeFam; TF314243; -.
DR   Proteomes; UP000001595; Chromosome 12.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.
DR   InterPro; IPR019311; DUF2362.
DR   PANTHER; PTHR16525; PTHR16525; 1.
DR   Pfam; PF10154; DUF2362; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..552
FT                   /note="Protein C12orf4 homolog"
FT                   /id="PRO_0000089844"
FT   REGION          383..403
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   552 AA;  63887 MW;  7CE39DC1A4391DB5 CRC64;
     MKKNRERFCN REREFVYKFK VGSQCLELRV PLRFPVQENA SHLHGRLMLL HSLPCFIEKD
     LKEALTQFIE EESLSDYDRD AEASLEAVKS GEVDLHQLAS TWAKAYAETT LEHARPEEPS
     WDEDFADVYH DLIHSPASET LLNLEHNYFV SISELIGERD VELKKLRERQ GIEMEKVMQE
     LGKSLTDQDV NSLAAQHFES QQDLENKWSN ELKQSTAIQK QEYQEWVIKL HQDLKNPNNS
     SLSEEIKVQP SQFRESVEAI GRIYEEQRKL EESFTIHLGA QLKTMHNLRL LRADMLDFCK
     HKRNHRSGVK LHRLQTALSL YSTSLCGLVL LVDNRINSYS GIKRDFATVC QECTDFHFPR
     IEEQLEVVQQ VVLYARTQRR SKLKESLDSG NQNGGNDDKT KNAERNYLNV LPGEFYITRH
     SNLSEIHVAF HLCVDDHVKS GNITARDPAI MGLRNILKVC CTHDITTISI PLLLVHDMSE
     EMTIPWCLRR AELVFKCVKG FMMEMASWDG GISRTVQFLV PQSISEEMFY QLSNMLPQIF
     RVSSTLTLTS KH