CL029_MOUSE
ID CL029_MOUSE Reviewed; 327 AA.
AC Q8BHN7; Q8BHP8; Q8BHV9;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Uncharacterized protein C12orf29 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Bone, Brain, and Embryo;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=C57BL/6J; TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8BHN7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8BHN7-2; Sequence=VSP_028320, VSP_028321;
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DR EMBL; AK032226; BAC27770.1; -; mRNA.
DR EMBL; AK036647; BAE43296.1; -; mRNA.
DR EMBL; AK078231; BAC37184.1; -; mRNA.
DR EMBL; AK082894; BAC38673.1; -; mRNA.
DR EMBL; BC082587; AAH82587.1; -; mRNA.
DR CCDS; CCDS24151.1; -. [Q8BHN7-1]
DR RefSeq; NP_780337.2; NM_175128.2. [Q8BHN7-1]
DR AlphaFoldDB; Q8BHN7; -.
DR STRING; 10090.ENSMUSP00000062410; -.
DR iPTMnet; Q8BHN7; -.
DR PhosphoSitePlus; Q8BHN7; -.
DR EPD; Q8BHN7; -.
DR MaxQB; Q8BHN7; -.
DR PaxDb; Q8BHN7; -.
DR PeptideAtlas; Q8BHN7; -.
DR PRIDE; Q8BHN7; -.
DR Antibodypedia; 52241; 118 antibodies from 23 providers.
DR Ensembl; ENSMUST00000054471; ENSMUSP00000062410; ENSMUSG00000046567. [Q8BHN7-1]
DR GeneID; 68281; -.
DR KEGG; mmu:68281; -.
DR UCSC; uc007gxx.2; mouse. [Q8BHN7-1]
DR UCSC; uc007gxy.2; mouse. [Q8BHN7-2]
DR MGI; MGI:1921197; 4930430F08Rik.
DR VEuPathDB; HostDB:ENSMUSG00000046567; -.
DR eggNOG; ENOG502QWBV; Eukaryota.
DR GeneTree; ENSGT00500000044938; -.
DR HOGENOM; CLU_074918_0_0_1; -.
DR InParanoid; Q8BHN7; -.
DR OMA; GTCCYVS; -.
DR OrthoDB; 804376at2759; -.
DR PhylomeDB; Q8BHN7; -.
DR TreeFam; TF328501; -.
DR BioGRID-ORCS; 68281; 1 hit in 72 CRISPR screens.
DR PRO; PR:Q8BHN7; -.
DR Proteomes; UP000000589; Chromosome 10.
DR RNAct; Q8BHN7; protein.
DR Bgee; ENSMUSG00000046567; Expressed in spermatocyte and 240 other tissues.
DR ExpressionAtlas; Q8BHN7; baseline and differential.
DR Genevisible; Q8BHN7; MM.
DR GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IGI:MGI.
DR InterPro; IPR041211; DUF5565.
DR PANTHER; PTHR31219; PTHR31219; 1.
DR Pfam; PF17720; DUF5565; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..327
FT /note="Uncharacterized protein C12orf29 homolog"
FT /id="PRO_0000305273"
FT VAR_SEQ 265..273
FT /note="HRHHLGLCW -> MTRNNLSLF (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_028320"
FT VAR_SEQ 274..327
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_028321"
FT CONFLICT 224
FT /note="F -> L (in Ref. 1; BAC27770)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 327 AA; 37418 MW; AFD17FCE7129FBD4 CRC64;
MKRLGSVQRK MPCVFVTEVK AEPSAKREHQ PFKVLATETL SEKALDADVY NAVATEKVDG
TCCYVTNYKG QPYLWARLDR KPNKQADKRF KKFLHSKESA KEFHWNTEED FKPVPECWIP
AKEIEKQNGK PVPDENGHIP GWVPVEKGSK QYCWHSSVVN YEFGIALVLR HHPDDPGVLE
ISAVPLSELL EQTLELIGTS INGNPYGLGS KKSPLHFLTP HGAFQVRNLP TLKHNDLLSW
FEDCREGQIE GIVWHCGDGC LIKVHRHHLG LCWPLPDTYM NSKPVIINMN LNLNNYDCAF
DNQSLFNQFS KIDKQKFERL KDIILDV
