CL060_MOUSE
ID CL060_MOUSE Reviewed; 247 AA.
AC Q810N5; Q8C8R6;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Uncharacterized protein C12orf60 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Retina;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK044622; BAC32007.1; -; mRNA.
DR EMBL; BC049715; AAH49715.1; -; mRNA.
DR CCDS; CCDS39685.1; -.
DR RefSeq; NP_848891.2; NM_178776.3.
DR RefSeq; XP_006506325.1; XM_006506262.3.
DR RefSeq; XP_006506326.1; XM_006506263.3.
DR RefSeq; XP_006506327.1; XM_006506264.3.
DR RefSeq; XP_006506328.1; XM_006506265.3.
DR RefSeq; XP_006506329.1; XM_006506266.2.
DR RefSeq; XP_017177123.1; XM_017321634.1.
DR RefSeq; XP_017177124.1; XM_017321635.1.
DR RefSeq; XP_017177125.1; XM_017321636.1.
DR AlphaFoldDB; Q810N5; -.
DR SMR; Q810N5; -.
DR iPTMnet; Q810N5; -.
DR PhosphoSitePlus; Q810N5; -.
DR EPD; Q810N5; -.
DR PaxDb; Q810N5; -.
DR PRIDE; Q810N5; -.
DR Antibodypedia; 51929; 39 antibodies from 11 providers.
DR DNASU; 320135; -.
DR Ensembl; ENSMUST00000052702; ENSMUSP00000049512; ENSMUSG00000047515.
DR Ensembl; ENSMUST00000163640; ENSMUSP00000133266; ENSMUSG00000047515.
DR Ensembl; ENSMUST00000203499; ENSMUSP00000145015; ENSMUSG00000047515.
DR GeneID; 320135; -.
DR KEGG; mmu:320135; -.
DR UCSC; uc009emi.2; mouse.
DR MGI; MGI:3605234; BC049715.
DR VEuPathDB; HostDB:ENSMUSG00000047515; -.
DR eggNOG; ENOG502S734; Eukaryota.
DR GeneTree; ENSGT00390000003800; -.
DR HOGENOM; CLU_1124225_0_0_1; -.
DR InParanoid; Q810N5; -.
DR OMA; LMKFPIM; -.
DR OrthoDB; 1399012at2759; -.
DR PhylomeDB; Q810N5; -.
DR TreeFam; TF338464; -.
DR BioGRID-ORCS; 320135; 1 hit in 72 CRISPR screens.
DR PRO; PR:Q810N5; -.
DR Proteomes; UP000000589; Chromosome 6.
DR RNAct; Q810N5; protein.
DR Bgee; ENSMUSG00000047515; Expressed in humerus cartilage element and 57 other tissues.
DR ExpressionAtlas; Q810N5; baseline and differential.
DR InterPro; IPR027895; DUF4533.
DR Pfam; PF15047; DUF4533; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..247
FT /note="Uncharacterized protein C12orf60 homolog"
FT /id="PRO_0000274272"
FT REGION 161..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 92..95
FT /note="TAMT -> PAVI (in Ref. 1; BAC32007)"
FT /evidence="ECO:0000305"
FT CONFLICT 115
FT /note="R -> G (in Ref. 1; BAC32007)"
FT /evidence="ECO:0000305"
FT CONFLICT 143
FT /note="M -> T (in Ref. 1; BAC32007)"
FT /evidence="ECO:0000305"
FT CONFLICT 171
FT /note="T -> I (in Ref. 1; BAC32007)"
FT /evidence="ECO:0000305"
FT CONFLICT 239
FT /note="F -> S (in Ref. 1; BAC32007)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 247 AA; 28062 MW; 2481ED16B5C32DA8 CRC64;
MSSESEKDKE RLIQAAKLFF FHIRDLVSFI NRFVELFNLT MKTQILPMNL NEESCIKDFF
EQMIRNFKEM QLMVDGKHKQ MQKEPLCSKV LTAMTSAVEK CATIAPHHTA EDMLRNIQTS
GAALVLKTSH VLVNLETSLS LLMQFPIMGL RLSDLYREET KEQSDATSDA TTSEKNKSPE
CPKATTEETL RKLQDVLSPE NAHTPVEAAA DELEQFVKSM EITLQVLQKS IKTMEGDIFV
LTQVQGK