CL071_MOUSE
ID CL071_MOUSE Reviewed; 301 AA.
AC Q80W69; Q8C629; Q8CDR6; Q9D9Q1;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Uncharacterized protein C12orf71 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q80W69-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q80W69-2; Sequence=VSP_034616;
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DR EMBL; AK006598; BAB24668.1; -; mRNA.
DR EMBL; AK029686; BAC26563.1; -; mRNA.
DR EMBL; AK076643; BAC36432.1; -; mRNA.
DR EMBL; BC052362; AAH52362.1; -; mRNA.
DR CCDS; CCDS51956.1; -. [Q80W69-2]
DR CCDS; CCDS51957.1; -. [Q80W69-1]
DR RefSeq; NP_001157708.1; NM_001164236.1. [Q80W69-2]
DR RefSeq; NP_082785.1; NM_028509.1. [Q80W69-1]
DR RefSeq; XP_006507175.1; XM_006507112.3. [Q80W69-1]
DR RefSeq; XP_011239934.1; XM_011241632.2. [Q80W69-1]
DR RefSeq; XP_017177265.1; XM_017321776.1. [Q80W69-1]
DR AlphaFoldDB; Q80W69; -.
DR STRING; 10090.ENSMUSP00000043802; -.
DR iPTMnet; Q80W69; -.
DR PhosphoSitePlus; Q80W69; -.
DR PaxDb; Q80W69; -.
DR PRIDE; Q80W69; -.
DR Antibodypedia; 49080; 4 antibodies from 4 providers.
DR Ensembl; ENSMUST00000036592; ENSMUSP00000043802; ENSMUSG00000040163. [Q80W69-1]
DR Ensembl; ENSMUST00000111622; ENSMUSP00000107249; ENSMUSG00000040163. [Q80W69-2]
DR GeneID; 73344; -.
DR KEGG; mmu:73344; -.
DR UCSC; uc009eso.2; mouse. [Q80W69-1]
DR UCSC; uc012evt.1; mouse. [Q80W69-2]
DR MGI; MGI:1920594; 1700034J05Rik.
DR VEuPathDB; HostDB:ENSMUSG00000040163; -.
DR eggNOG; ENOG502RTYV; Eukaryota.
DR GeneTree; ENSGT00390000018322; -.
DR HOGENOM; CLU_081160_0_0_1; -.
DR InParanoid; Q80W69; -.
DR OMA; WVFRWLR; -.
DR OrthoDB; 558442at2759; -.
DR TreeFam; TF338465; -.
DR BioGRID-ORCS; 73344; 2 hits in 72 CRISPR screens.
DR PRO; PR:Q80W69; -.
DR Proteomes; UP000000589; Chromosome 6.
DR RNAct; Q80W69; protein.
DR Bgee; ENSMUSG00000040163; Expressed in interventricular septum and 33 other tissues.
DR Genevisible; Q80W69; MM.
DR InterPro; IPR027908; DUF4640.
DR PANTHER; PTHR36462; PTHR36462; 1.
DR Pfam; PF15480; DUF4640; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..301
FT /note="Uncharacterized protein C12orf71 homolog"
FT /id="PRO_0000343578"
FT REGION 167..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 220
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_034616"
FT CONFLICT 57
FT /note="F -> I (in Ref. 1; BAB24668)"
FT /evidence="ECO:0000305"
FT CONFLICT 164
FT /note="Q -> H (in Ref. 1; BAC26563)"
FT /evidence="ECO:0000305"
FT CONFLICT 180
FT /note="Q -> H (in Ref. 1; BAC26563)"
FT /evidence="ECO:0000305"
FT CONFLICT 199
FT /note="E -> Q (in Ref. 1; BAC26563)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 301 AA; 34755 MW; BCC4AC5E70EA8AAA CRC64;
MTTSPSSSDY SSTEDSIYEC KSNQSASVGY YPSENTFSYE DLVSREETAS VDSLVHFLPP
VQSTWRTESL RRLFRKRDQV EHDPEQFSKL SITLAWDIDV DSNHADSLAN LDLNAHSQWM
DKWPEDKTKL TPCKLYNLVQ KLETFLGKEK GGQHDGCVLP ESTQKEDVHL NSTTPPHTAQ
VSPKERDVCQ DLSKQRSLEN EDICQVLEDP PRLLKDEVVQ EIRQASESSL ETSSVSSPQP
EGASRSHNIF CMNFRWVFQW LRTQIFSRWR RQRPSQATNT WHQKAVRNIH SLRSNRIQPQ
E
