ID   CL160_CAEEL             Reviewed;         639 AA.
AC   P34393; Q8MNT5;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2004, sequence version 2.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=C-type lectin domain-containing protein 160;
DE   Flags: Precursor;
GN   Name=clec-160; ORFNames=F09G8.8;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; FO080289; CCD62647.1; -; Genomic_DNA.
DR   PIR; S44792; S44792.
DR   RefSeq; NP_498819.2; NM_066418.5.
DR   AlphaFoldDB; P34393; -.
DR   SMR; P34393; -.
DR   STRING; 6239.F09G8.8; -.
DR   EPD; P34393; -.
DR   PaxDb; P34393; -.
DR   PeptideAtlas; P34393; -.
DR   PRIDE; P34393; -.
DR   EnsemblMetazoa; F09G8.8.1; F09G8.8.1; WBGene00017322.
DR   GeneID; 176167; -.
DR   KEGG; cel:CELE_F09G8.8; -.
DR   CTD; 176167; -.
DR   WormBase; F09G8.8; CE33579; WBGene00017322; clec-160.
DR   eggNOG; ENOG502RWBE; Eukaryota.
DR   HOGENOM; CLU_432965_0_0_1; -.
DR   InParanoid; P34393; -.
DR   OMA; GICFLDQ; -.
DR   OrthoDB; 412541at2759; -.
DR   PhylomeDB; P34393; -.
DR   PRO; PR:P34393; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00017322; Expressed in adult organism and 2 other tissues.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0030246; F:carbohydrate binding; IBA:GO_Central.
DR   Gene3D; 3.10.100.10; -; 1.
DR   Gene3D; 3.40.50.410; -; 2.
DR   InterPro; IPR001304; C-type_lectin-like.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF00059; Lectin_C; 1.
DR   Pfam; PF00092; VWA; 2.
DR   SMART; SM00034; CLECT; 1.
DR   SMART; SM00327; VWA; 2.
DR   SUPFAM; SSF53300; SSF53300; 2.
DR   SUPFAM; SSF56436; SSF56436; 1.
DR   PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
DR   PROSITE; PS50234; VWFA; 2.
PE   3: Inferred from homology;
KW   Disulfide bond; Lectin; Reference proteome; Repeat; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..639
FT                   /note="C-type lectin domain-containing protein 160"
FT                   /id="PRO_0000014280"
FT   DOMAIN          31..178
FT                   /note="VWFA 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00219"
FT   DOMAIN          289..474
FT                   /note="VWFA 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00219"
FT   DOMAIN          491..618
FT                   /note="C-type lectin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT   DISULFID        594..614
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
SQ   SEQUENCE   639 AA;  71489 MW;  100D27CE88FF0508 CRC64;
     MDLKSWILLS CTLLPLSVTS YECYVTPCTR DIIIVVDGSS SMQTSTYVSQ EINMITKLTY
     SWTLDDAKVR LALVGAYLGN EFNGLDYFTD SSLIEKRLQS FRLAAMQYGL FSGDFNTTVR
     FLDERYVGPR ATFGPRANVQ KRIIIFSAHK GASDIASTKS KLQEFAQLGY AVTIVGIGVS
     EDVYKGTFYH KFVSVQWFEL GVVAQSIIDT ITEDGICFLD QGWTTPKQEI CTTSTTTTRA
     PTTTTTVTTV KGVTGKPATT AKPVPPTHPP FPVGDYQDCS CTTQSLYIDI IFVIDVSEGM
     GQGGLMMVKA EINTLVGQMS LDPNIQKHVQ VGLIKYSDKA EVVFKPSDYT NEDEFTEDLW
     SDPRLEDVDE KSDEVNLHLG LQQAAKMTAS MRNGVRKVIV VYAASYNDEG NDDARQIAAN
     IRETGYAIIT VAFVEPESSN LVMKIGEIAS PRMNFTSFRD DLLVEQMEDA LCQVNCYCPN
     GWKQLVLENR KYGECFFPTK IDASWTASKF ECPVLSKEHT GNGHLVYVNS ELKNTFLNQF
     YMDNWYPENQ ENPNYDIGYY YDQATKKFIW VNGVTNNPYS NWATGHPDVK QGDCVMAKLL
     KDSKNDFRWN SVSCTSEYGR GLCQEAACDT DFYCAPSSN