ID   CL2DR_RAT               Reviewed;         235 AA.
AC   Q5M9I1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=C-type lectin domain family 2 member D-related protein;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Lectin-type cell surface receptor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type II
CC       membrane protein {ECO:0000250}.
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DR   EMBL; BC086997; AAH86997.1; -; mRNA.
DR   RefSeq; NP_001019508.1; NM_001024337.1.
DR   RefSeq; XP_006237499.1; XM_006237437.3.
DR   RefSeq; XP_006237500.1; XM_006237438.3.
DR   RefSeq; XP_008761544.1; XM_008763322.2.
DR   RefSeq; XP_017448537.1; XM_017593048.1.
DR   RefSeq; XP_017458358.1; XM_017602869.1.
DR   AlphaFoldDB; Q5M9I1; -.
DR   SMR; Q5M9I1; -.
DR   STRING; 10116.ENSRNOP00000050011; -.
DR   GlyGen; Q5M9I1; 1 site.
DR   PaxDb; Q5M9I1; -.
DR   PRIDE; Q5M9I1; -.
DR   Ensembl; ENSRNOT00000043078; ENSRNOP00000050011; ENSRNOG00000030522.
DR   GeneID; 500331; -.
DR   KEGG; rno:500331; -.
DR   UCSC; RGD:1564464; rat.
DR   RGD; 1564464; LOC500331.
DR   VEuPathDB; HostDB:ENSRNOG00000048726; -.
DR   eggNOG; KOG4297; Eukaryota.
DR   GeneTree; ENSGT00940000155319; -.
DR   InParanoid; Q5M9I1; -.
DR   OrthoDB; 1289964at2759; -.
DR   PhylomeDB; Q5M9I1; -.
DR   TreeFam; TF351467; -.
DR   PRO; PR:Q5M9I1; -.
DR   Proteomes; UP000002494; Chromosome 4.
DR   Bgee; ENSRNOG00000030522; Expressed in testis and 18 other tissues.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IBA:GO_Central.
DR   CDD; cd03593; CLECT_NK_receptors_like; 1.
DR   Gene3D; 3.10.100.10; -; 1.
DR   InterPro; IPR001304; C-type_lectin-like.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR033992; NKR-like_CTLD.
DR   Pfam; PF00059; Lectin_C; 1.
DR   SMART; SM00034; CLECT; 1.
DR   SUPFAM; SSF56436; SSF56436; 1.
DR   PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; Lectin; Membrane; Receptor;
KW   Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix.
FT   CHAIN           1..235
FT                   /note="C-type lectin domain family 2 member D-related
FT                   protein"
FT                   /id="PRO_0000315297"
FT   TOPO_DOM        1..75
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        97..235
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          121..232
FT                   /note="C-type lectin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        134
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   235 AA;  26114 MW;  F19DB355B5673AD3 CRC64;
     MPSSAHLQDP PPHLSRTLTQ DEEQTSLRQS SSCGPSTTSA SASESLSGST KSRISQKKLL
     EGMLPKIIPT ESAAKLLCCY AVFMALTVVV IALSIALSVK KTPQISAVNT YAACQRNWIG
     FGNKCYYFNE TARNWTFSQT LCKEQEAELA RFDNEEELNF LKRYKGSSGY WIGLHRESSA
     DPWKWTDNTA YNNLVPIKGE EKHGFLSDNG LSSGKDYIKR KSICSKLNSY TSQCP