ID   ACHB_CHICK              Reviewed;         118 AA.
AC   P16005;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Acetylcholine receptor subunit beta;
DE   Flags: Precursor; Fragment;
GN   Name=CHRNB1;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2584213; DOI=10.1016/s0021-9258(19)47047-6;
RA   Moss S.J., Darlison M.G., Beeson D.M.W., Barnard E.A.;
RT   "Development expression of the genes encoding the four subunits of the
RT   chicken muscle acetylcholine receptor.";
RL   J. Biol. Chem. 264:20199-20205(1989).
CC   -!- FUNCTION: After binding acetylcholine, the AChR responds by an
CC       extensive change in conformation that affects all subunits and leads to
CC       opening of an ion-conducting channel across the plasma membrane.
CC   -!- SUBUNIT: Pentamer of two alpha chains, and one each of the beta, delta,
CC       and gamma chains.
CC   -!- SUBCELLULAR LOCATION: Postsynaptic cell membrane; Multi-pass membrane
CC       protein. Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
CC       Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-1/CHRNB1 sub-
CC       subfamily. {ECO:0000305}.
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DR   EMBL; M31494; AAA48562.1; -; mRNA.
DR   PIR; A32673; A32673.
DR   AlphaFoldDB; P16005; -.
DR   SMR; P16005; -.
DR   ComplexPortal; CPX-254; Muscle-type nicotinic acetylcholine receptor complex, alpha1-beta1-delta-gamma.
DR   InParanoid; P16005; -.
DR   PhylomeDB; P16005; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005892; C:acetylcholine-gated channel complex; IC:ComplexPortal.
DR   GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045202; C:synapse; IEA:GOC.
DR   GO; GO:0022848; F:acetylcholine-gated cation-selective channel activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0095500; P:acetylcholine receptor signaling pathway; IC:ComplexPortal.
DR   Gene3D; 2.70.170.10; -; 1.
DR   InterPro; IPR006202; Neur_chan_lig-bd.
DR   InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR   InterPro; IPR006201; Neur_channel.
DR   InterPro; IPR002394; Nicotinic_acetylcholine_rcpt.
DR   PANTHER; PTHR18945; PTHR18945; 1.
DR   Pfam; PF02931; Neur_chan_LBD; 1.
DR   PRINTS; PR00254; NICOTINICR.
DR   SUPFAM; SSF63712; SSF63712; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Ion channel; Ion transport; Ligand-gated ion channel;
KW   Membrane; Postsynaptic cell membrane; Receptor; Reference proteome; Signal;
KW   Synapse; Transmembrane; Transport.
FT   SIGNAL          <1..15
FT   CHAIN           16..>118
FT                   /note="Acetylcholine receptor subunit beta"
FT                   /id="PRO_0000000318"
FT   NON_TER         1
FT   NON_TER         118
SQ   SEQUENCE   118 AA;  12627 MW;  0E1854F2346BE138 CRC64;
     APTVALLLLC ALCSAADAPP PPPSAAASAD GAYHAGVRPA PTPRDRVEVR VGLSLAQLVS
     LDEKNEELTT KVYLDLSWWD PRLQWDPHDY GGLGGLRVAA SRLWLPDIGL DNNNDGEF