ACHB_ELEEL
ID ACHB_ELEEL Reviewed; 24 AA.
AC P09689;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1989, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Acetylcholine receptor subunit beta;
DE Flags: Fragment;
GN Name=chrnb1;
OS Electrophorus electricus (Electric eel) (Gymnotus electricus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Gymnotiformes;
OC Gymnotoidei; Gymnotidae; Electrophorus.
OX NCBI_TaxID=8005;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=6959131; DOI=10.1073/pnas.79.21.6489;
RA Conti-Tronconi B.M., Hunkapiller M.W., Lindstrom J.M., Raftery M.A.;
RT "Subunit structure of the acetylcholine receptor from Electrophorus
RT electricus.";
RL Proc. Natl. Acad. Sci. U.S.A. 79:6489-6493(1982).
CC -!- FUNCTION: After binding acetylcholine, the AChR responds by an
CC extensive change in conformation that affects all subunits and leads to
CC opening of an ion-conducting channel across the plasma membrane.
CC -!- SUBUNIT: Pentamer of two alpha chains, and one each of the beta, delta,
CC and gamma chains.
CC -!- SUBCELLULAR LOCATION: Postsynaptic cell membrane; Multi-pass membrane
CC protein. Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
CC Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-1/CHRNB1 sub-
CC subfamily. {ECO:0000305}.
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DR PIR; B27262; B27262.
DR AlphaFoldDB; P09689; -.
DR STRING; 8005.ENSEEEP00000002378; -.
DR Proteomes; UP000314983; Unassembled WGS sequence.
DR GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Cell membrane; Direct protein sequencing; Ion channel; Ion transport;
KW Ligand-gated ion channel; Membrane; Postsynaptic cell membrane; Receptor;
KW Reference proteome; Synapse; Transmembrane; Transport.
FT CHAIN 1..>24
FT /note="Acetylcholine receptor subunit beta"
FT /id="PRO_0000076977"
FT NON_TER 24
SQ SEQUENCE 24 AA; 2766 MW; 2D8E1B0F4A2F20AF CRC64;
SEAENDLMNK LFTAYNPKVR PAEK