CLBA1_HUMAN
ID CLBA1_HUMAN Reviewed; 325 AA.
AC Q96F83; B2RPK9; Q9BTP4;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Uncharacterized protein CLBA1 {ECO:0000305};
DE AltName: Full=Clathrin-binding box of aftiphilin-containing protein 1 {ECO:0000312|HGNC:HGNC:20126};
GN Name=CLBA1 {ECO:0000312|HGNC:HGNC:20126}; Synonyms=C14orf79;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12508121; DOI=10.1038/nature01348;
RA Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H.,
RA Du H., Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T.,
RA Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B.,
RA Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D.,
RA Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R.,
RA Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S.,
RA Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C.,
RA Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S.,
RA Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C.,
RA Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P.,
RA Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J.,
RA Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F.,
RA Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F.,
RA Waterston R., Hood L., Weissenbach J.;
RT "The DNA sequence and analysis of human chromosome 14.";
RL Nature 421:601-607(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex, and Pancreas;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AL512802; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471061; EAW81892.1; -; Genomic_DNA.
DR EMBL; BC003539; AAH03539.1; -; mRNA.
DR EMBL; BC137495; AAI37496.1; -; mRNA.
DR CCDS; CCDS42000.1; -.
DR RefSeq; NP_777551.2; NM_174891.3.
DR AlphaFoldDB; Q96F83; -.
DR BioGRID; 125781; 3.
DR IntAct; Q96F83; 1.
DR STRING; 9606.ENSP00000450114; -.
DR iPTMnet; Q96F83; -.
DR PhosphoSitePlus; Q96F83; -.
DR BioMuta; CLBA1; -.
DR DMDM; 125863840; -.
DR MassIVE; Q96F83; -.
DR PaxDb; Q96F83; -.
DR PeptideAtlas; Q96F83; -.
DR PRIDE; Q96F83; -.
DR ProteomicsDB; 76500; -.
DR Antibodypedia; 54950; 33 antibodies from 9 providers.
DR DNASU; 122616; -.
DR Ensembl; ENST00000547315.6; ENSP00000450114.1; ENSG00000140104.14.
DR GeneID; 122616; -.
DR KEGG; hsa:122616; -.
DR MANE-Select; ENST00000547315.6; ENSP00000450114.1; NM_174891.4; NP_777551.2.
DR UCSC; uc001ypy.2; human.
DR CTD; 122616; -.
DR GeneCards; CLBA1; -.
DR HGNC; HGNC:20126; CLBA1.
DR HPA; ENSG00000140104; Low tissue specificity.
DR neXtProt; NX_Q96F83; -.
DR OpenTargets; ENSG00000140104; -.
DR PharmGKB; PA134876308; -.
DR VEuPathDB; HostDB:ENSG00000140104; -.
DR eggNOG; ENOG502SPS5; Eukaryota.
DR GeneTree; ENSGT00940000154186; -.
DR HOGENOM; CLU_071310_0_1_1; -.
DR InParanoid; Q96F83; -.
DR OMA; LWSESHC; -.
DR OrthoDB; 922964at2759; -.
DR PhylomeDB; Q96F83; -.
DR TreeFam; TF335916; -.
DR PathwayCommons; Q96F83; -.
DR SignaLink; Q96F83; -.
DR BioGRID-ORCS; 122616; 9 hits in 1048 CRISPR screens.
DR GeneWiki; C14orf79; -.
DR GenomeRNAi; 122616; -.
DR Pharos; Q96F83; Tdark.
DR PRO; PR:Q96F83; -.
DR Proteomes; UP000005640; Chromosome 14.
DR RNAct; Q96F83; protein.
DR Bgee; ENSG00000140104; Expressed in right uterine tube and 118 other tissues.
DR ExpressionAtlas; Q96F83; baseline and differential.
DR Genevisible; Q96F83; HS.
DR GO; GO:0030121; C:AP-1 adaptor complex; IBA:GO_Central.
DR GO; GO:0032588; C:trans-Golgi network membrane; IBA:GO_Central.
DR GO; GO:0030276; F:clathrin binding; IBA:GO_Central.
DR GO; GO:0046907; P:intracellular transport; IBA:GO_Central.
DR InterPro; IPR046359; Aftin-like.
DR InterPro; IPR029205; Clathrin-bd.
DR PANTHER; PTHR16156; PTHR16156; 1.
DR Pfam; PF15045; Clathrin_bdg; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..325
FT /note="Uncharacterized protein CLBA1"
FT /id="PRO_0000274387"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 51..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 92..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 35690 MW; EDA4C63C1F4D1571 CRC64;
MQGRRELGGE PLSDLQEEAA SASLRVAPER LSDDSLEWRR TCPDLLLSDG KASISMPREG
GSTCTARCPD PGEHSSTWGE FEGFRESSAK SGQFSQSLEL LEGPTEPQPP RTTSAPKECS
SHQPCQGGPW VTGTSAVPPS EPILSYENIL KCAFQEITVQ QAAEDVSTID HFLEISSEEK
PGVERVHKLC NESRKLWRAL QSIHTTSTSQ RLWSESRCQE NFFLVLGIDA AQKNLSGGQG
HIMEDCDLKE PEGLLTVSSF CLQHCKALIQ TKLSGPPGSK QGRLMTCSRF LKTPSCGGGQ
HITIPRKRMF TPRKLKLTLF NSDVC
