ID   CLC2F_MOUSE             Reviewed;         196 AA.
AC   Q8VI21;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=C-type lectin domain family 2 member F;
DE   AltName: Full=C-type lectin-related protein C;
DE            Short=Clr-c;
GN   Name=Clec2f; Synonyms=Clrc;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=11398965; DOI=10.1007/s002510100319;
RA   Plougastel B., Dubbelde C., Yokoyama W.M.;
RT   "Cloning of Clr, a new family of lectin-like genes localized between mouse
RT   Nkrp1a and Cd69.";
RL   Immunogenetics 53:209-214(2001).
CC   -!- FUNCTION: Lectin-type cell surface receptor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type II
CC       membrane protein {ECO:0000250}.
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DR   EMBL; AF320596; AAL37197.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8VI21; -.
DR   SMR; Q8VI21; -.
DR   GlyGen; Q8VI21; 1 site.
DR   iPTMnet; Q8VI21; -.
DR   PhosphoSitePlus; Q8VI21; -.
DR   PRIDE; Q8VI21; -.
DR   ProteomicsDB; 279100; -.
DR   MGI; MGI:3522133; Clec2f.
DR   InParanoid; Q8VI21; -.
DR   PRO; PR:Q8VI21; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q8VI21; protein.
DR   GO; GO:0009986; C:cell surface; ISO:MGI.
DR   GO; GO:0005783; C:endoplasmic reticulum; ISO:MGI.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IBA:GO_Central.
DR   CDD; cd03593; CLECT_NK_receptors_like; 1.
DR   Gene3D; 3.10.100.10; -; 1.
DR   InterPro; IPR001304; C-type_lectin-like.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR033992; NKR-like_CTLD.
DR   Pfam; PF00059; Lectin_C; 1.
DR   SMART; SM00034; CLECT; 1.
DR   SUPFAM; SSF56436; SSF56436; 1.
DR   PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; Glycoprotein; Lectin; Membrane;
KW   Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix.
FT   CHAIN           1..196
FT                   /note="C-type lectin domain family 2 member F"
FT                   /id="PRO_0000315288"
FT   TOPO_DOM        1..41
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..62
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        63..196
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          84..187
FT                   /note="C-type lectin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        97
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        77..88
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT   DISULFID        105..186
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
SQ   SEQUENCE   196 AA;  22205 MW;  2504DA7A46BF3C6A CRC64;
     MNAQCLKKPE EGESSPGTGD KILQRNSLRA ISPESSAKLY CCCGVIMVLT VAVVALSVAL
     PATKTEQILI NKTYAACPKN WIGVGNKCFY FSEYTSNWTF AQTFCMAQEA QLARFDNEKE
     LNFLKRHMNS SHWIGLHRDS SEHPWRWTDN TEYNNTFLIQ GDGECGFLSD NGISSSRDYI
     PRKWICSRSS NYMLQC