ID   CLCL_RALSO              Reviewed;         429 AA.
AC   Q8XTT4;
DT   05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   23-APR-2003, sequence version 2.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Putative chloride channel protein ClcB-like;
GN   OrderedLocusNames=RSp0020; ORFNames=RS01992;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OG   Plasmid megaplasmid Rsp.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family. ClcB
CC       subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAD17171.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL646053; CAD17171.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q8XTT4; -.
DR   SMR; Q8XTT4; -.
DR   STRING; 267608.RSp0020; -.
DR   EnsemblBacteria; CAD17171; CAD17171; RSp0020.
DR   KEGG; rso:RSp0020; -.
DR   eggNOG; COG0038; Bacteria.
DR   HOGENOM; CLU_015263_5_2_4; -.
DR   OMA; GPLTMTF; -.
DR   Proteomes; UP000001436; Plasmid megaplasmid Rsp.
DR   GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   GO; GO:0010447; P:response to acidic pH; IEA:InterPro.
DR   HAMAP; MF_01203; CLC_ClcB; 1.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   InterPro; IPR023790; Cl-channel_volt-gated_ClcB.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF81340; SSF81340; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Chloride; Chloride channel;
KW   Ion channel; Ion transport; Membrane; Plasmid; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Voltage-gated channel.
FT   CHAIN           1..429
FT                   /note="Putative chloride channel protein ClcB-like"
FT                   /id="PRO_0000094493"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        259..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        354..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        383..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   429 AA;  44195 MW;  5159534BAAE9ED79 CRC64;
     MLAIAGLIGC AGALATIAFR ECLRQLQWWL AGADQGLVAT ARALPWWARL LVPTAGGLLA
     GLTLQYGLKW IPRKGAEDYM EAIAVGDGVL SARQSLVRSA SSLCSVASGA SIGREGPMVQ
     LAAMCGSLLG RVLRHAMPVS VEHMRLLVAC GAAAGITSAY NAPIAGAVFV CEIVFGAITT
     ATLGPLLVSA VTADIIVRQF FGYGAVYAMP HFDFVSGWEV LTYLGLGLAA GMAGPLLLGL
     IDRARGAFAR TRLPQALRLA LGGLIVGALS IRVPEVWGNG YSVVNGFLHA PWLWQTVALV
     LVCKVGATAA SAGSGAVGGV FTPTLFCGAA LGLLYGTGMH ALLPGAAPVP VSYAVVGMGA
     LLAATTHAPL MSILMIFEMT LSYQVVLPLM LACITGYVTA HATGAPSVYA RALARNRDDT
     LRLPPASSP