ID   CLDN1_MACFA             Reviewed;         253 AA.
AC   Q4R4Z3;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Claudin domain-containing protein 1;
GN   Name=CLDND1; ORFNames=QnpA-16207;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Parietal cortex;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family. {ECO:0000305}.
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DR   EMBL; AB169751; BAE01832.1; -; mRNA.
DR   RefSeq; XP_005548395.2; XM_005548338.2.
DR   RefSeq; XP_005548398.1; XM_005548341.2.
DR   RefSeq; XP_005548399.1; XM_005548342.2.
DR   RefSeq; XP_005548400.1; XM_005548343.2.
DR   RefSeq; XP_005548401.1; XM_005548344.2.
DR   RefSeq; XP_015302044.1; XM_015446558.1.
DR   RefSeq; XP_015302045.1; XM_015446559.1.
DR   RefSeq; XP_015302046.1; XM_015446560.1.
DR   RefSeq; XP_015302047.1; XM_015446561.1.
DR   RefSeq; XP_015302048.1; XM_015446562.1.
DR   AlphaFoldDB; Q4R4Z3; -.
DR   STRING; 9541.XP_005548395.1; -.
DR   Ensembl; ENSMFAT00000099914; ENSMFAP00000052770; ENSMFAG00000041563.
DR   GeneID; 101925141; -.
DR   KEGG; mcf:101925141; -.
DR   CTD; 56650; -.
DR   VEuPathDB; HostDB:ENSMFAG00000041563; -.
DR   eggNOG; ENOG502QRAV; Eukaryota.
DR   GeneTree; ENSGT00390000002596; -.
DR   Proteomes; UP000233100; Chromosome 2.
DR   Bgee; ENSMFAG00000041563; Expressed in frontal cortex and 13 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR042356; CLDN1.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   PANTHER; PTHR14347; PTHR14347; 1.
DR   Pfam; PF13903; Claudin_2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..253
FT                   /note="Claudin domain-containing protein 1"
FT                   /id="PRO_0000273423"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        42
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        72
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   253 AA;  28576 MW;  FD3CAD23B28C830F CRC64;
     MDNRFATAFV IACVLSLIST IYMAASIGTD FWYEYRSPVQ ENSSDLNKSI WDEFISDEAD
     EKTYNDALFR YNGTVGLWRR CITIPKNMHW YSPPERTESF DVVTKCVSFT LTEQFMEKFV
     DPGNHNSGID LLRTYLWRCQ FLLPFVSLGL MCFGALIGLC ACICRSLYPT IATGILHLLA
     GLCTLGSVSC YVAGIELLHQ KLELPDSVSG EFGWSFCLAC VSAPLQFMAS ALFIWAAHTN
     RKEYTLMKAY RVA