ID   CLF1_MAGO7              Reviewed;         691 AA.
AC   Q527H0; A4RQ48; G4MPG7;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Pre-mRNA-splicing factor CLF1;
GN   Name=CLF1; ORFNames=MGG_05720;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Involved in pre-mRNA splicing and cell cycle progression.
CC       Required for the spliceosome assembly and initiation of the DNA
CC       replication (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the crooked-neck family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM001231; EHA58010.1; -; Genomic_DNA.
DR   RefSeq; XP_003710622.1; XM_003710574.1.
DR   AlphaFoldDB; Q527H0; -.
DR   SMR; Q527H0; -.
DR   STRING; 318829.MGG_05720T0; -.
DR   PRIDE; Q527H0; -.
DR   EnsemblFungi; MGG_05720T0; MGG_05720T0; MGG_05720.
DR   GeneID; 2675972; -.
DR   KEGG; mgr:MGG_05720; -.
DR   VEuPathDB; FungiDB:MGG_05720; -.
DR   eggNOG; KOG1915; Eukaryota.
DR   HOGENOM; CLU_011554_1_0_1; -.
DR   InParanoid; Q527H0; -.
DR   OMA; HIKVWIS; -.
DR   OrthoDB; 355408at2759; -.
DR   Proteomes; UP000009058; Chromosome 1.
DR   GO; GO:0000785; C:chromatin; IEA:EnsemblFungi.
DR   GO; GO:0000974; C:Prp19 complex; IEA:EnsemblFungi.
DR   GO; GO:0071006; C:U2-type catalytic step 1 spliceosome; IEA:EnsemblFungi.
DR   GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; IEA:EnsemblFungi.
DR   GO; GO:0071008; C:U2-type post-mRNA release spliceosomal complex; IEA:EnsemblFungi.
DR   GO; GO:0071004; C:U2-type prespliceosome; IEA:EnsemblFungi.
DR   GO; GO:0003682; F:chromatin binding; IEA:EnsemblFungi.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:EnsemblFungi.
DR   GO; GO:0000354; P:cis assembly of pre-catalytic spliceosome; IEA:EnsemblFungi.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:EnsemblFungi.
DR   Gene3D; 1.25.40.10; -; 4.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR045075; Syf1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR11246; PTHR11246; 1.
DR   Pfam; PF02184; HAT; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00386; HAT; 15.
DR   SUPFAM; SSF48452; SSF48452; 4.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Repeat;
KW   Spliceosome.
FT   CHAIN           1..691
FT                   /note="Pre-mRNA-splicing factor CLF1"
FT                   /id="PRO_0000205747"
FT   REPEAT          52..84
FT                   /note="HAT 1"
FT   REPEAT          86..118
FT                   /note="HAT 2"
FT   REPEAT          120..152
FT                   /note="HAT 3"
FT   REPEAT          154..185
FT                   /note="HAT 4"
FT   REPEAT          187..218
FT                   /note="HAT 5"
FT   REPEAT          220..258
FT                   /note="HAT 6"
FT   REPEAT          260..294
FT                   /note="HAT 7"
FT   REPEAT          304..336
FT                   /note="HAT 8"
FT   REPEAT          338..372
FT                   /note="HAT 9"
FT   REPEAT          382..418
FT                   /note="HAT 10"
FT   REPEAT          420..451
FT                   /note="HAT 11"
FT   REPEAT          453..485
FT                   /note="HAT 12"
FT   REPEAT          487..521
FT                   /note="HAT 13"
FT   REPEAT          523..554
FT                   /note="HAT 14"
FT   REPEAT          574..612
FT                   /note="HAT 15"
FT   REPEAT          617..650
FT                   /note="HAT 16"
SQ   SEQUENCE   691 AA;  82325 MW;  DD231D256AEEEBC2 CRC64;
     MEASRGPPRV KNKAAAPVQI SAEQLLREAT DRQEEALQKP TQRFEDLEEL HEYQGRKRKE
     FESYCQRSGF NLKNWLQYAQ WELEQKEYAR SRSVFERALN LHANKVTLWI RYVEAELKSR
     NINFARNLLD RAVTHLPRVD KLWYKYVWVE EMLGNIPGVR QVFERWMEWQ PDEAAWSAFI
     KLEQRYGEYD RAREIFTRFT MVHPEPRNWI KWSKFEEEYG TSDRVREVFE RAIEELSKYG
     DEFVEERLFI AYARYEAKLH DLDRARAIYK FGLENLPRSK AMLLHKEYTT FEKQYGDREG
     VEDVVLSKRR RHYEDLVREN PKNYDVWFDY ARLEEASGDI DRTREVYEKA IAQVPPTQAK
     RHWRRYIYLW IFFALWEETE AKNPERARQV YDTCLKLIPH RTFTFAKVWM HKAHFEIRQG
     DLAAARKTLG RAIGMCPKDR LFKGYIEMEQ KLYEFGRCRI LYEKHIAYNP ANCSTWVKWA
     ELERGLDDLD RARAILDMGI AQPVLDMPEV VWKSYIDFEE EEGEYDKTRS LYERLLDKAD
     HPKVWISYAQ FEINIPEEAG EGADEEQEQP VSDEAKARAR RVFERAHQGF KDKEMKAERV
     SILNAWLVFE KTHGSAEDIE KIEKQMPRRT KKKRKLDDDT WEEYVDYIFP ADEQVGKNLM
     NMMAKARARK QAEAEAAAKA AAADDGGESG E