CLPC1_ORYSJ
ID CLPC1_ORYSJ Reviewed; 918 AA.
AC Q7F9I1; Q0JDK8;
DT 21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT 21-SEP-2011, sequence version 2.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Chaperone protein ClpC1, chloroplastic;
DE AltName: Full=ATP-dependent Clp protease ATP-binding subunit ClpC homolog 1;
DE AltName: Full=Casein lytic proteinase C1;
DE Flags: Precursor;
GN Name=CLPC1; OrderedLocusNames=Os04g0397100, LOC_Os04g32560;
GN ORFNames=OSJNBa0039C07.4;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=20141629; DOI=10.1186/1471-2164-11-95;
RA Singh A., Singh U., Mittal D., Grover A.;
RT "Genome-wide analysis of rice ClpB/HSP100, ClpC and ClpD genes.";
RL BMC Genomics 11:95-95(2010).
CC -!- FUNCTION: Molecular chaperone that may interact with a ClpP-like
CC protease involved in degradation of denatured proteins in the
CC chloroplast. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:20141629}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family. ClpC subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF14579.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAE05148.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AL731591; CAE05148.2; ALT_INIT; Genomic_DNA.
DR EMBL; AP008210; BAF14579.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015635530.1; XM_015780044.1.
DR AlphaFoldDB; Q7F9I1; -.
DR SMR; Q7F9I1; -.
DR BioGRID; 804739; 1.
DR STRING; 4530.OS04T0397100-01; -.
DR PaxDb; Q7F9I1; -.
DR PRIDE; Q7F9I1; -.
DR GeneID; 4335702; -.
DR KEGG; osa:4335702; -.
DR eggNOG; KOG1051; Eukaryota.
DR InParanoid; Q7F9I1; -.
DR OrthoDB; 611758at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 1.10.1780.10; -; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
DR SUPFAM; SSF81923; SSF81923; 1.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Chaperone; Chloroplast; Nucleotide-binding; Plastid;
KW Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..?
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN ?..918
FT /note="Chaperone protein ClpC1, chloroplastic"
FT /id="PRO_0000412579"
FT DOMAIN 88..230
FT /note="Clp R"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT DOMAIN 505..540
FT /note="UVR"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00217"
FT REGION 91..156
FT /note="Repeat 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT REGION 166..230
FT /note="Repeat 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT REGION 251..498
FT /note="I"
FT /evidence="ECO:0000250"
FT REGION 565..756
FT /note="II"
FT /evidence="ECO:0000250"
FT BINDING 296..303
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
FT BINDING 639..646
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 918 AA; 101802 MW; 85A3DDBD677BBBEB CRC64;
MEGSLVQSAI APTIYRRSGT ARFRVRARAT MMRTMPTRTL TLGGFQGLRQ TNFLDSRSVI
KRDFGSIVAS QISRPRGLGS RGVVRAMFER FTEKAIKVIM LAQEEARRLG HNFVGTEQIL
LGLIGEGTGI AAKVLKSMGI NLKDARVEVE KIIGRGSGFV AVEIPFTPRA KRVLELSLEE
ARQLGHNYIG SEHLLLGLLR EGEGVAARVL ESLGADPNNI RTQVIRMVGE STEAVGAGVG
GGSSGQKMPT LEEYGTNLTK LAEEGKLDPV VGRQDQIERV TQILGRRTKN NPCLIGEPGV
GKTAIAEGLA QRISNGDVPE TIEGKKVITL DMGLLVAGTK YRGEFEERLK KLMEEIKQND
DIILFIDEVH TLIGAGAAEG AIDAANILKP ALARGELQCI GATTLDEYRK HIEKDPALER
RFQPVKVPEP TVDETIQILR GLRERYELHH KLRYTDDSLI AAAQLSYQYI SDRFLPDKAI
DLIDEAGSRV RLRHAQLPDE AKELDKELRQ VTKDKNEAVR GQDFEKAGEL RDREMELKAQ
ITAIIDKSKE MVKAETESGE VGPLVTEADI QHIVSSWTGI PVEKVSSDES DRLLKMEETL
HTRIIGQDEA VKAISRAIRR ARVGLKNPNR PIASFIFSGP TGVGKSELAK ALAAYYFGSE
EAMIRLDMSE FMERHTVSKL IGSPPGYVGY TEGGQLTEAV RRRPYTVVLF DEIEKAHPDV
FNMMLQILED GRLTDSKGRT VDFKNTLLIM TSNVGSSVIE KGGRKIGFDL DYDEKDTSYN
RIKSLVTEEL KQYFRPEFLN RLDEMIVFRQ LTKLEVKEIA DIMLKEVFDR LKAKDIDLQV
TEKFRDRVVD EGYNPSYGAR PLRRAIMRLL EDSLAEKMLA GEVKEGDSAI VDVDSEGKVI
VLNGGSGVPE PLAPALSV
