CLPC2_ORYSJ
ID CLPC2_ORYSJ Reviewed; 919 AA.
AC Q2QVG9; A0A0P0Y8B5;
DT 21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Chaperone protein ClpC2, chloroplastic;
DE AltName: Full=ATP-dependent Clp protease ATP-binding subunit ClpC homolog 2;
DE AltName: Full=Casein lytic proteinase C2;
DE Flags: Precursor;
GN Name=CLPC2; OrderedLocusNames=Os12g0230100, LOC_Os12g12850;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Molecular chaperone that may interact with a ClpP-like
CC protease involved in degradation of denatured proteins in the
CC chloroplast. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family. ClpC subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK066153; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; DP000011; ABA96309.2; -; Genomic_DNA.
DR EMBL; DP000011; ABG21929.1; -; Genomic_DNA.
DR EMBL; AP008218; BAF29461.1; -; Genomic_DNA.
DR EMBL; AP014968; BAT16428.1; -; Genomic_DNA.
DR EMBL; AK066153; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015620084.1; XM_015764598.1.
DR RefSeq; XP_015620085.1; XM_015764599.1.
DR AlphaFoldDB; Q2QVG9; -.
DR SMR; Q2QVG9; -.
DR STRING; 4530.OS12T0230100-01; -.
DR PaxDb; Q2QVG9; -.
DR PRIDE; Q2QVG9; -.
DR EnsemblPlants; Os12t0230100-01; Os12t0230100-01; Os12g0230100.
DR GeneID; 4351828; -.
DR Gramene; Os12t0230100-01; Os12t0230100-01; Os12g0230100.
DR KEGG; osa:4351828; -.
DR eggNOG; KOG1051; Eukaryota.
DR HOGENOM; CLU_005070_4_1_1; -.
DR InParanoid; Q2QVG9; -.
DR OMA; HIERDMA; -.
DR OrthoDB; 611758at2759; -.
DR Proteomes; UP000000763; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR Genevisible; Q2QVG9; OS.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 1.10.1780.10; -; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
DR SUPFAM; SSF81923; SSF81923; 1.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Chaperone; Chloroplast; Nucleotide-binding; Plastid;
KW Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..54
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 55..919
FT /note="Chaperone protein ClpC2, chloroplastic"
FT /id="PRO_0000412580"
FT DOMAIN 89..231
FT /note="Clp R"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT DOMAIN 506..541
FT /note="UVR"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00217"
FT REGION 92..157
FT /note="Repeat 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT REGION 167..231
FT /note="Repeat 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT REGION 252..499
FT /note="I"
FT /evidence="ECO:0000250"
FT REGION 566..757
FT /note="II"
FT /evidence="ECO:0000250"
FT BINDING 297..304
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
FT BINDING 640..647
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 919 AA; 102017 MW; 33F171C85CF0E6E2 CRC64;
MAGTLLQPVA LGTTFAGRVS GQRWKSHGTR RPPSMLAMSL SRPVKMAAFV GLRSVHSFSV
TPVTNFRSTV ASYRSRRGRR ARFVTRSMFE RFTEKAIKVI MLAQEEARRL GHNFVGTEQI
LLGLIGEGTG IAAKVLKSMG INLKDARVEV EKIIGRGNGF VAVEIPFTPR AKRVLELSLE
EARQLGHNYI GSEHLLLGLL REGEGVAARV LESLGADPSN IRTQVIRMIG ETTEAVGAGV
GGGSSGNKMP TLEEYGTNLT KLAEEGKLDP VVGRQPQIER VVQILGRRTK NNPCLIGEPG
VGKTAIAEGL AQRISTGDVP ETIEGKKVIT LDMGLLVAGT KYRGEFEERL KKLMEEIKQS
DEIILFIDEV HTLIGAGAAE GAIDAANILK PALARGELQC IGATTLDEYR KHIEKDPALE
RRFQPVRVPE PTVDETIEIL RGLRERYEIH HKLRYTDDAL ISAAKLSYQY ISDRFLPDKA
IDLIDEAGSR VRLRHAQVPE EARELDKELK QITKDKNEAV RSQDFEKAGE LRDREMELKA
QITALIDKSK EMSKAETESG ETGPLVNEAD IQHIVSSWTG IPVEKVSSDE SDKLLKMEET
LHQRVIGQDE AVKAISRSIR RARVGLKNPN RPIASFIFAG PTGVGKSELA KALAAYYFGS
EEAMIRLDMS EFMERHTVSK LIGSPPGYVG YTEGGQLTEA VRRRPYTVVL FDEIEKAHPD
VFNMMLQILE DGRLTDSKGR TVDFKNTLLI MTSNVGSSVI EKGGRKIGFD LDYDEKDSSY
SRIKSLVVEE MKQYFRPEFL NRLDEMIVFR QLTKLEVKEI AEIMLKEVFD RLKAKDIDLQ
VTEKFKERIV DEGFNPSYGA RPLRRAIMRL LEDSLAEKML AGEVKEGDSA IVDVDSEGKV
IVLNGQSGLP ELSTPAVTV
