ID   CLPC_CHLTR              Reviewed;         854 AA.
AC   O84288;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Probable ATP-dependent Clp protease ATP-binding subunit;
GN   Name=clpC; OrderedLocusNames=CT_286;
OS   Chlamydia trachomatis (strain D/UW-3/Cx).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=272561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D/UW-3/Cx;
RX   PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA   Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA   Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT   "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT   trachomatis.";
RL   Science 282:754-759(1998).
CC   -!- SIMILARITY: Belongs to the ClpA/ClpB family. ClpC subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE001273; AAC67879.1; -; Genomic_DNA.
DR   PIR; C71533; C71533.
DR   RefSeq; NP_219791.1; NC_000117.1.
DR   RefSeq; WP_010725148.1; NC_000117.1.
DR   AlphaFoldDB; O84288; -.
DR   SMR; O84288; -.
DR   STRING; 813.O172_01540; -.
DR   PRIDE; O84288; -.
DR   EnsemblBacteria; AAC67879; AAC67879; CT_286.
DR   GeneID; 884839; -.
DR   KEGG; ctr:CT_286; -.
DR   PATRIC; fig|272561.5.peg.306; -.
DR   HOGENOM; CLU_005070_4_1_0; -.
DR   InParanoid; O84288; -.
DR   OMA; ERMKAVM; -.
DR   Proteomes; UP000000431; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 1.10.1780.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR004176; Clp_R_dom.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001943; UVR_dom.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF02861; Clp_N; 2.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   SUPFAM; SSF81923; SSF81923; 1.
DR   PROSITE; PS51903; CLP_R; 1.
DR   PROSITE; PS50151; UVR; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Reference proteome; Repeat.
FT   CHAIN           1..854
FT                   /note="Probable ATP-dependent Clp protease ATP-binding
FT                   subunit"
FT                   /id="PRO_0000191232"
FT   DOMAIN          2..145
FT                   /note="Clp R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   DOMAIN          443..478
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00217"
FT   REGION          5..70
FT                   /note="Repeat 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   REGION          81..145
FT                   /note="Repeat 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   REGION          151..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         234..241
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   BINDING         571..578
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   854 AA;  95146 MW;  7AD3FA9914B1D189 CRC64;
     MFEKFTNRAK QVIKLAKKEA QRLNHNYLGT EHILLGLLKL GQGVAVNVLR TLGVDFDTAK
     HEVERLIGYG PEIQVCGDPA LTGRVKKSFE SANEEAALLE HNYVGTEHLL LGILNQSDGV
     ALQVLENLHV DPKEIRKEIL KELETFNLQL PPSSSITPRN TNSSSSSKSS SPLGGHTLGG
     DKPEKLSALK AYGYDLTEMF KESRLDPVIG RSAEVERLIL ILCRRRKNNP VLVGEAGVGK
     TAIVEGLAQK IVSGEVPEAL RKKRLITLDL ALMIAGTKYR GQFEERIKAV MDEVRKHGNI
     LLFIDELHTI VGAGAAEGAI DASHILKPAL ARGEIQCIGA TTLDEYRKHI EKDAALERRF
     QKIVVQPPSV DETVEILRGL KKKYEEHHNV FITDEALVAA AKLSDQYVHG RFLPDKAIDL
     LDEAGARVRV NTMGQPSDLV RLEAEIEKTK QAKEQAIGTQ EYEKAASLRD EEKKLREKLG
     NMKQQWESNK EEHQVPVDEE AVAQVVSVQT GIPAARLTEA ESEKLLTLET TLQKKVIGQS
     QAVASICRAI RRSRTGIKDP NRPMGSFLFL GPTGVGKTLL AQQIAIEMFG GEDSLIQVDM
     SEYMEKFAAT KMMGSPPGYV GHEEGGHLTE QVRRRPYCVV LFDEIEKAHP DIMDLMLQIL
     EQGRLTDSFG RKIDFRNTII IMTSNLGADL IRKSGEIGFG LRSHMDYAVI KEKIDAAVKK
     HLKPEFINRL DESVIFKPLE KEALSEIIHL EINKLGSRLQ NYQMDLNIPD SVISFLVTKG
     HSPEMGARPL RRVVEQYLED PLAEMLLKES CRQEARKLRA RLTEERVVFE REEEAVSALA
     IEGDGSEPIT ADES