ID   CLPC_CYACA              Reviewed;         854 AA.
AC   Q9TM05;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA homolog;
GN   Name=clpC;
OS   Cyanidium caldarium (Red alga).
OG   Plastid; Chloroplast.
OC   Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae; Cyanidium.
OX   NCBI_TaxID=2771;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RK-1;
RX   PubMed=11040290; DOI=10.1007/s002390010101;
RA   Gloeckner G., Rosenthal A., Valentin K.-U.;
RT   "The structure and gene repertoire of an ancient red algal plastid
RT   genome.";
RL   J. Mol. Evol. 51:382-390(2000).
CC   -!- FUNCTION: May interact with a ClpP-like protease involved in
CC       degradation of denatured proteins in the chloroplast.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
CC   -!- SIMILARITY: Belongs to the ClpA/ClpB family. {ECO:0000305}.
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DR   EMBL; AF022186; AAF12982.1; -; Genomic_DNA.
DR   RefSeq; NP_045112.1; NC_001840.1.
DR   AlphaFoldDB; Q9TM05; -.
DR   SMR; Q9TM05; -.
DR   PRIDE; Q9TM05; -.
DR   GeneID; 800182; -.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 1.10.1780.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR004176; Clp_R_dom.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR028299; ClpA/B_CS2.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001943; UVR_dom.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF02861; Clp_N; 2.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   SUPFAM; SSF81923; SSF81923; 1.
DR   PROSITE; PS51903; CLP_R; 1.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS00871; CLPAB_2; 1.
DR   PROSITE; PS50151; UVR; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Chloroplast; Nucleotide-binding; Plastid; Repeat.
FT   CHAIN           1..854
FT                   /note="ATP-dependent Clp protease ATP-binding subunit ClpA
FT                   homolog"
FT                   /id="PRO_0000191216"
FT   DOMAIN          33..175
FT                   /note="Clp R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   DOMAIN          447..482
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00217"
FT   REGION          36..101
FT                   /note="Repeat 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   REGION          111..175
FT                   /note="Repeat 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   BINDING         238..245
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   BINDING         579..586
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   854 AA;  95633 MW;  E66546F0DC5CC401 CRC64;
     MNIQPNTFFL KAMLTLLNIK GNNMCWAHKK NMFERFTEKA VKVIMLAQEE ARRLGHNFVG
     TEQILLGILG EGTGLAAKAL KSMGITLKDA RIEVEKIIGR GSGFVAIEIP FTPRAKKILE
     LAIEESRILT HNYVGTEHLL LGLIKEGEGV AARVLENLGV DLPKLRSNII RMIGETSEVS
     VGATSGRSKV PTLEEFGTNL TQMAVEGKLD PVVGRAKEIE RVVQILGRRT KNNPVLIGEP
     GVGKTAIAEG LAQRIINNEV PDTLEDKKVI TLDVSLLVAG TKYRGEFEER LKKIMDEIRM
     ADNVILVIDE VHTLIGAGAA EGAIDAANIL KPALARGELQ CIGATTLEEY RKHIEKDAAL
     ERRFQPVMVE EPTVEETIEI LRGLRDRYEA HHRLKISDSA IVAAAKLSDQ YIADRFLPDK
     AIDLVDEASS RVRLMNYKLP PSAEYLDEEL RHIQKIKNEL IRSGDFEEAS QFREREIEVK
     VQMAALMKAK KEAIEEELAL NPPIVNEDDI ANIVSSWTGI PVSKLTKSES EKLLHMEETL
     HSRIVGQNEA VIAVSKAIRR ARVGLKNPNR PIASFIFSGP TGVGKTELTK AMASYFFGSE
     EAMVRLDMSE YMERHTVSKL IGSPPGYVGY NEGGQLTEAV RKRPYTVVLF DEIEKAHPDV
     FNLLLQILED GRLTDSKGRT IDFKNTLLIM TSNIGSKVIE KKGGGLGFEL EENIEELQYS
     RMRNLVNEEL KQYFRPEFLN RVDEIIVFRQ LTKDEVRDIA HIMLREIFER VKQQGISLQV
     TERFKNLLIE EGYNPSYGAR PLRRALVRLL EDSLAEEVLS GKIKEGDNAM IDVDENKQVK
     ILLGNSNNQH AFLA