ID   CLPD1_ORYSJ             Reviewed;         938 AA.
AC   Q6H795; A0A0P0VJZ7;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Chaperone protein ClpD1, chloroplastic {ECO:0000305};
DE   AltName: Full=ATP-dependent Clp protease ATP-binding subunit ClpD homolog 1 {ECO:0000305};
DE   AltName: Full=Casein lytic proteinase D1 {ECO:0000303|PubMed:27457985};
DE   Flags: Precursor;
GN   Name=CLPD1 {ECO:0000303|PubMed:20141629};
GN   OrderedLocusNames=Os02g0526400 {ECO:0000312|EMBL:BAF08911.1},
GN   LOC_Os02g32520 {ECO:0000305};
GN   ORFNames=P0458B05.10 {ECO:0000312|EMBL:BAD25404.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   INDUCTION.
RX   PubMed=16924117; DOI=10.1073/pnas.0604882103;
RA   Hu H., Dai M., Yao J., Xiao B., Li X., Zhang Q., Xiong L.;
RT   "Overexpressing a NAM, ATAF, and CUC (NAC) transcription factor enhances
RT   drought resistance and salt tolerance in rice.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:12987-12992(2006).
RN   [5]
RP   FUNCTION, TISSUE SPECIFICITY, AND INDUCTION BY LOW TEMPERATURE.
RX   PubMed=20141629; DOI=10.1186/1471-2164-11-95;
RA   Singh A., Singh U., Mittal D., Grover A.;
RT   "Genome-wide analysis of rice ClpB/HSP100, ClpC and ClpD genes.";
RL   BMC Genomics 11:95-95(2010).
RN   [6]
RP   FUNCTION.
RX   PubMed=27457985; DOI=10.1016/j.plantsci.2016.06.004;
RA   Mishra R.C., Richa X., Grover A.;
RT   "Constitutive over-expression of rice ClpD1 protein enhances tolerance to
RT   salt and desiccation stresses in transgenic Arabidopsis plants.";
RL   Plant Sci. 250:69-78(2016).
CC   -!- FUNCTION: Molecular chaperone that may function in heat stress
CC       response. May interact with a ClpP-like protease involved in
CC       degradation of denatured proteins in the chloroplast (PubMed:20141629).
CC       Chaperone involved in response to abiotic stresses. Plays a positive
CC       role during dehydration and salt stress (PubMed:27457985).
CC       {ECO:0000269|PubMed:20141629, ECO:0000269|PubMed:27457985}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in stems, culms and leaves.
CC       {ECO:0000269|PubMed:20141629}.
CC   -!- INDUCTION: Induced by low temperature (PubMed:20141629). Induced by
CC       drought stress, salt stress and abscisic acid (PubMed:16924117).
CC       {ECO:0000269|PubMed:16924117, ECO:0000269|PubMed:20141629}.
CC   -!- MISCELLANEOUS: Plants overexpressing CLPD1 exhibit improved tolerance
CC       to drought and salt stresses. {ECO:0000269|PubMed:27457985}.
CC   -!- SIMILARITY: Belongs to the ClpA/ClpB family. ClpD subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAS78991.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP004777; BAD25404.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF08911.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS78991.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_015625492.1; XM_015770006.1.
DR   AlphaFoldDB; Q6H795; -.
DR   SMR; Q6H795; -.
DR   STRING; 4530.OS02T0526400-01; -.
DR   PaxDb; Q6H795; -.
DR   PRIDE; Q6H795; -.
DR   GeneID; 4329520; -.
DR   KEGG; osa:4329520; -.
DR   eggNOG; KOG1051; Eukaryota.
DR   HOGENOM; CLU_005070_4_1_1; -.
DR   InParanoid; Q6H795; -.
DR   OrthoDB; 611758at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6H795; OS.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0034605; P:cellular response to heat; IMP:UniProtKB.
DR   GO; GO:1901002; P:positive regulation of response to salt stress; IMP:UniProtKB.
DR   GO; GO:1902584; P:positive regulation of response to water deprivation; IMP:UniProtKB.
DR   Gene3D; 1.10.1780.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR004176; Clp_R_dom.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR028299; ClpA/B_CS2.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF02861; Clp_N; 2.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   SUPFAM; SSF81923; SSF81923; 1.
DR   PROSITE; PS51903; CLP_R; 1.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS00871; CLPAB_2; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Chaperone; Chloroplast; Nucleotide-binding; Plastid;
KW   Reference proteome; Repeat; Stress response; Transit peptide.
FT   TRANSIT         1..83
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           84..938
FT                   /note="Chaperone protein ClpD1, chloroplastic"
FT                   /id="PRO_0000412583"
FT   DOMAIN          84..224
FT                   /note="Clp R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   REGION          84..145
FT                   /note="Repeat 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   REGION          159..224
FT                   /note="Repeat 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   REGION          234..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          266..519
FT                   /note="I"
FT                   /evidence="ECO:0000250"
FT   REGION          586..777
FT                   /note="II"
FT                   /evidence="ECO:0000250"
FT   BINDING         311..318
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   BINDING         660..667
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   938 AA;  101884 MW;  DEB149CC5E073AC0 CRC64;
     MEVCCCSTSS AVPGRRFAAA GAAAAAVAAR WGAVGVGRAV VLAHPLRPAP RGGHAHAQQA
     GARRARRAVV RAVFERFTER AVKAVVLSQR EAKGLGEGAV APRHLLLGLI AEDRSAGGFL
     SSGINIERAR EECRGIGARD LTPGAPSPSG SGLEMDIPFS GSCKRVFEVA VEFSRNMGCS
     FISPEHLALA LFTLDDPTTN SLLRSLGADP SQLASVALTR LQAELAKDCR EPAGASSFKV
     PKKSPAGAGR SAFSKSLNSK KEKGALDQFC LDLTTQASGG FIDPIIGREE EIERVVQIIC
     RRTKNNPILL GEAGVGKTAI AEGLALRIAN GDVPIYLVAK RIMSLDVGLL IAGAKERGEL
     ESRVTSLIRE VREAGDVILF IDEVHNLIGS GTVGKGKGAG LDIGNLLKPP LARGELQCIA
     ATTLDEHRMH FEKDKALARR FQPVLVEEPS QDDAVKILLG LREKYETYHK CKFTLEAINA
     AVYLSARYIP DRQLPDKAID LIDEAGSRAR MESFNRKKEG QSSILLKSPD EYWQEIRAAQ
     NMHEVVSSNQ MKYSPRQENG SAAIKAPSED MNELTSELQV EEPIVVGTEE IARVASLWSG
     IPVQQLTADD RKLLVGLDGE LRKRVIGQDD AVMAISRAVK RSRVGLNDPD RPIATLLFCG
     PTGVGKTELT KALAASYFGS ESAMLRLDMS EYMERHTVSK LIGSPPGYIG YGETGTLTEA
     VRRKPFTVVL LDEIEKAHPD IFNILLQIFE DGHLSDSQGR RVSFKNTLIV MTSNIGSTSI
     SKGRRSMGFM TEDTESSSYV AMKSLVMEEL KAFFRPELLN RIDEMVVFRP LEKTQMLAIL
     DIILQEVKGR LLALGIGLEV SDAMKDLICE EGYDKSYGAR PLRRAVTHLI EDVISEAILF
     GEYKPGDTIL MDIDAGGKLC MSHLNEKVVQ LSDPTRTF