ID   CLPD2_ORYSJ             Reviewed;         937 AA.
AC   Q7XL03; Q0JDG6;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 2.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Chaperone protein ClpD2, chloroplastic;
DE   AltName: Full=ATP-dependent Clp protease ATP-binding subunit ClpD homolog 2;
DE   AltName: Full=Casein lytic proteinase D2;
DE   Flags: Precursor;
GN   Name=CLPD2; OrderedLocusNames=Os04g0405000, LOC_Os04g33210;
GN   ORFNames=OJ000315_02.14;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   TISSUE SPECIFICITY.
RX   PubMed=20141629; DOI=10.1186/1471-2164-11-95;
RA   Singh A., Singh U., Mittal D., Grover A.;
RT   "Genome-wide analysis of rice ClpB/HSP100, ClpC and ClpD genes.";
RL   BMC Genomics 11:95-95(2010).
CC   -!- FUNCTION: Molecular chaperone that may interact with a ClpP-like
CC       protease involved in degradation of denatured proteins in the
CC       chloroplast. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Highly expressed in stems, culms and leaves.
CC       {ECO:0000269|PubMed:20141629}.
CC   -!- SIMILARITY: Belongs to the ClpA/ClpB family. ClpD subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF14621.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=CAE05369.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AL731639; CAE05369.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008210; BAF14621.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015636344.1; XM_015780858.1.
DR   AlphaFoldDB; Q7XL03; -.
DR   SMR; Q7XL03; -.
DR   STRING; 39947.Q7XL03; -.
DR   PaxDb; Q7XL03; -.
DR   PRIDE; Q7XL03; -.
DR   GeneID; 4335747; -.
DR   KEGG; osa:4335747; -.
DR   InParanoid; Q7XL03; -.
DR   OrthoDB; 611758at2759; -.
DR   Proteomes; UP000000763; Chromosome 4.
DR   Proteomes; UP000059680; Chromosome 4.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 1.10.1780.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR004176; Clp_R_dom.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR028299; ClpA/B_CS2.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF02861; Clp_N; 2.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   SUPFAM; SSF81923; SSF81923; 1.
DR   PROSITE; PS51903; CLP_R; 1.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS00871; CLPAB_2; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Chaperone; Chloroplast; Nucleotide-binding; Plastid;
KW   Reference proteome; Repeat; Transit peptide.
FT   TRANSIT         1..80
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           81..937
FT                   /note="Chaperone protein ClpD2, chloroplastic"
FT                   /id="PRO_0000412584"
FT   DOMAIN          81..217
FT                   /note="Clp R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   REGION          81..137
FT                   /note="Repeat 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   REGION          152..217
FT                   /note="Repeat 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT   REGION          259..513
FT                   /note="I"
FT                   /evidence="ECO:0000250"
FT   REGION          584..775
FT                   /note="II"
FT                   /evidence="ECO:0000250"
FT   BINDING         304..311
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   BINDING         658..665
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   937 AA;  101484 MW;  1D36CD0A322C0E86 CRC64;
     MEACCCSSSS VPSASILATG AGLRRRFSPA GAGGGGRAVA VAAGRPIRAS AALLAAPAPR
     RRGGVVVRAV FERFTERAVK AVVFSQREAR GMGDETVAPH HLLLGLVAED RSPLGFLASG
     VRVERAREAC RAAVGKEGLA QAPVGLATDV PFSGASKRVF EAAVEFSRNM GCNFISPEHI
     ALGLFNLNDP TTNNVLKSLG VDSSQLAKQA LTRVQGELAK DGREPVGLSS FKVREKFTPG
     GGKSAIVKYS NKNKEKSALA LFCLDLTMRA SGGLIDPVIG RKDEIERVVQ IICRRTKNNP
     ILLGEAGVGK TAIAEGLAHK IANGDVPIFL VGKRILSLDV ALLMAGAKER GELEARVTSL
     IREVRKAGDV ILFIDEVHTL IGSGIAGRGS KGAGLDIANL LKPALARGEL QCIASTTLDE
     HRLHFDKDKA LARRFQPVLV NEPSQEDAVK ILLGLREKYE TYHKCKYTLE SINAAVYLSA
     RYIADRHLPD KAIDLIDEAG SRARMESFKR KKEEQCSILS KSPDEYWQEI RAVQNMHEVA
     LTNKVKYSLN QNDQEDAVDI ELVGEDKTSP ASMLSTSTDK PSLVGSEEIA RVTSLWSGIP
     VQQLTADERK LLVGLDDELR KRVIGQDDAV LAISKAVKRS RVGLNDPDRP IATLIFCGPT
     GVGKTELTKA LAASYFGSES ATVRLDMSEY MERHAVSKLI GSPPGYMGFG EGGTLTEAVR
     RKPFTVVLLD EIEKAHPDIF NILLQIFEDG HLTDSQGRRV SFKNTLIVMT SNVGSTSISN
     GKRSIGFQTQ TDTEEKSYAA MKSLVMEELK AFFRPELLNR IDEVVVFHPL EKTQMLAILN
     IMLQEVKGRI LALGIGLEVS DSMKDLISQH GYDKSYGARP LRRAVTQLVE DVISEAILSG
     QFKPGDTIMV DTDATGKPCL SRLNDQTVQL SDPTPTL