CLPS_MYCTA
ID CLPS_MYCTA Reviewed; 101 AA.
AC A5U231;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=ATP-dependent Clp protease adapter protein ClpS {ECO:0000255|HAMAP-Rule:MF_00302};
GN Name=clpS {ECO:0000255|HAMAP-Rule:MF_00302}; OrderedLocusNames=MRA_1339;
OS Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=419947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25177 / H37Ra;
RX PubMed=18584054; DOI=10.1371/journal.pone.0002375;
RA Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L.,
RA Wang H., Wang S., Zhao G., Zhang Y.;
RT "Genetic basis of virulence attenuation revealed by comparative genomic
RT analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv.";
RL PLoS ONE 3:E2375-E2375(2008).
CC -!- FUNCTION: Involved in the modulation of the specificity of the ClpAP-
CC mediated ATP-dependent protein degradation. {ECO:0000255|HAMAP-
CC Rule:MF_00302}.
CC -!- SUBUNIT: Binds to the N-terminal domain of the chaperone ClpA.
CC {ECO:0000255|HAMAP-Rule:MF_00302}.
CC -!- SIMILARITY: Belongs to the ClpS family. {ECO:0000255|HAMAP-
CC Rule:MF_00302}.
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DR EMBL; CP000611; ABQ73081.1; -; Genomic_DNA.
DR RefSeq; WP_003406906.1; NZ_CP016972.1.
DR AlphaFoldDB; A5U231; -.
DR SMR; A5U231; -.
DR STRING; 419947.MRA_1339; -.
DR EnsemblBacteria; ABQ73081; ABQ73081; MRA_1339.
DR GeneID; 45425309; -.
DR KEGG; mra:MRA_1339; -.
DR eggNOG; COG2127; Bacteria.
DR HOGENOM; CLU_153743_1_0_11; -.
DR OMA; RDVQAMH; -.
DR OrthoDB; 1829294at2; -.
DR Proteomes; UP000001988; Chromosome.
DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1390.10; -; 1.
DR HAMAP; MF_00302; ClpS; 1.
DR InterPro; IPR022935; ClpS.
DR InterPro; IPR003769; ClpS_core.
DR InterPro; IPR014719; Ribosomal_L7/12_C/ClpS-like.
DR PANTHER; PTHR33473; PTHR33473; 1.
DR Pfam; PF02617; ClpS; 1.
DR SUPFAM; SSF54736; SSF54736; 1.
PE 3: Inferred from homology;
FT CHAIN 1..101
FT /note="ATP-dependent Clp protease adapter protein ClpS"
FT /id="PRO_0000300715"
SQ SEQUENCE 101 AA; 11222 MW; D78302CEC5FF5E5D CRC64;
MAVVSAPAKP GTTWQRESAP VDVTDRAWVT IVWDDPVNLM SYVTYVFQKL FGYSEPHATK
LMLQVHNEGK AVVSAGSRES MEVDVSKLHA AGLWATMQQD R