ID   CLUL1_BOVIN             Reviewed;         465 AA.
AC   Q3ZRW9;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Clusterin-like protein 1;
DE   Flags: Precursor;
GN   Name=CLUL1 {ECO:0000312|EMBL:AAT81475.1};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1] {ECO:0000312|EMBL:AAT81475.1}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Retinal cone cell {ECO:0000312|EMBL:AAT81475.1};
RA   Zhang Q., Tomita H., Anderson R.E.;
RT   "Further evidence showing CLUL1 as a conserved cone photoreceptor-specific
RT   gene.";
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the clusterin family. {ECO:0000255}.
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DR   EMBL; AY643094; AAT81475.1; -; mRNA.
DR   RefSeq; NP_001029692.1; NM_001034520.1.
DR   AlphaFoldDB; Q3ZRW9; -.
DR   SMR; Q3ZRW9; -.
DR   STRING; 9913.ENSBTAP00000018616; -.
DR   PaxDb; Q3ZRW9; -.
DR   PRIDE; Q3ZRW9; -.
DR   GeneID; 516801; -.
DR   KEGG; bta:516801; -.
DR   CTD; 27098; -.
DR   eggNOG; ENOG502QQ44; Eukaryota.
DR   InParanoid; Q3ZRW9; -.
DR   OrthoDB; 567684at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0051787; F:misfolded protein binding; IBA:GO_Central.
DR   InterPro; IPR000753; Clusterin-like.
DR   InterPro; IPR016015; Clusterin_C.
DR   InterPro; IPR016014; Clusterin_N.
DR   PANTHER; PTHR10970; PTHR10970; 1.
DR   Pfam; PF01093; Clusterin; 1.
DR   SMART; SM00035; CLa; 1.
DR   SMART; SM00030; CLb; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Disulfide bond; Glycoprotein; Reference proteome; Secreted;
KW   Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..465
FT                   /note="Clusterin-like protein 1"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000270977"
FT   REGION          280..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          62..107
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        196
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        257
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        311
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        351
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        412
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        430
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        105..333
FT                   /evidence="ECO:0000250|UniProtKB:P10909"
FT   DISULFID        116..325
FT                   /evidence="ECO:0000250|UniProtKB:P10909"
FT   DISULFID        119..322
FT                   /evidence="ECO:0000250|UniProtKB:P10909"
FT   DISULFID        124..315
FT                   /evidence="ECO:0000250|UniProtKB:P10909"
FT   DISULFID        131..305
FT                   /evidence="ECO:0000250|UniProtKB:P10909"
SQ   SEQUENCE   465 AA;  53950 MW;  9048047F34C086F3 CRC64;
     MKPPILVFIV YLLQLRDCQC APTGKDRTSI REDPKGFSKA GEIDVDEEVK KALIGMKQMK
     ILMERREEEH SKLMRTLKKC REEKQEALKL MNEVQEHLEE EERLCQVSLM DSWDECKSCL
     ESDCMRFYTT CQSSWSSMKS TIERVFRKIY QFLFPFHEDD EKELPVGEKF TEEDVQLMQI
     ENVFSQLTVD VGFLYNMSFH VFKQMQQEFD LAFQSYFMSD TDSMEPYFFP AFSKEPAKKA
     HPMQSWDIPS FFQLFCNFSL SVYQSVSATV TEMLKATEDL SKQDKDSAHG GPSSTTWPVR
     GRGLCGEPGQ NSSECLQFHA RCQKCQDYLW ADCPAVPELY TKADEALELV NISNQQYAQV
     LQMTQHHLED TTYLMEKMRE QFGWVTELAS QTPGSENIFS FIKVVPGVHE GNFSKQDEKM
     IDISILPSSN FTLTIPLEES AESSDFISYM LAKAVQHFKE HFKSW