ID   CLU_MAGO7               Reviewed;        1311 AA.
AC   A4R962; G4N8G4;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Clustered mitochondria protein homolog {ECO:0000255|HAMAP-Rule:MF_03013};
DE   AltName: Full=Protein TIF31 homolog {ECO:0000255|HAMAP-Rule:MF_03013};
GN   Name=CLU1 {ECO:0000255|HAMAP-Rule:MF_03013};
GN   Synonyms=TIF31 {ECO:0000255|HAMAP-Rule:MF_03013}; ORFNames=MGG_06261;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: mRNA-binding protein involved in proper cytoplasmic
CC       distribution of mitochondria. {ECO:0000255|HAMAP-Rule:MF_03013}.
CC   -!- SUBUNIT: May associate with the eukaryotic translation initiation
CC       factor 3 (eIF-3) complex. {ECO:0000255|HAMAP-Rule:MF_03013}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03013}.
CC   -!- SIMILARITY: Belongs to the CLU family. {ECO:0000255|HAMAP-
CC       Rule:MF_03013}.
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DR   EMBL; CM001234; EHA51012.1; -; Genomic_DNA.
DR   RefSeq; XP_003717331.1; XM_003717283.1.
DR   AlphaFoldDB; A4R962; -.
DR   SMR; A4R962; -.
DR   STRING; 318829.MGG_06261T0; -.
DR   PRIDE; A4R962; -.
DR   EnsemblFungi; MGG_06261T0; MGG_06261T0; MGG_06261.
DR   GeneID; 2684416; -.
DR   KEGG; mgr:MGG_06261; -.
DR   VEuPathDB; FungiDB:MGG_06261; -.
DR   eggNOG; KOG1839; Eukaryota.
DR   HOGENOM; CLU_003256_2_0_1; -.
DR   InParanoid; A4R962; -.
DR   OMA; VSGFYVN; -.
DR   OrthoDB; 60958at2759; -.
DR   Proteomes; UP000009058; Chromosome 4.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:UniProtKB-UniRule.
DR   GO; GO:0051640; P:organelle localization; IEA:UniProt.
DR   CDD; cd15466; CLU-central; 1.
DR   Gene3D; 1.25.40.10; -; 2.
DR   HAMAP; MF_03013; CLU; 1.
DR   InterPro; IPR033646; CLU-central.
DR   InterPro; IPR025697; CLU_dom.
DR   InterPro; IPR028275; CLU_N.
DR   InterPro; IPR027523; CLU_prot.
DR   InterPro; IPR023231; GSKIP_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR12601; PTHR12601; 1.
DR   Pfam; PF13236; CLU; 1.
DR   Pfam; PF15044; CLU_N; 1.
DR   Pfam; PF12807; eIF3_p135; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF103107; SSF103107; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS51823; CLU; 1.
DR   PROSITE; PS50005; TPR; 1.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..1311
FT                   /note="Clustered mitochondria protein homolog"
FT                   /id="PRO_0000366407"
FT   DOMAIN          324..568
FT                   /note="Clu"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01167"
FT   REPEAT          491..525
FT                   /note="TPR 1"
FT   REPEAT          1034..1067
FT                   /note="TPR 2"
FT   REPEAT          1076..1109
FT                   /note="TPR 3"
FT   REPEAT          1118..1151
FT                   /note="TPR 4"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          606..694
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          925..966
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1276..1311
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        606..632
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        633..658
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        659..694
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1311 AA;  145172 MW;  17CF2217EAED1157 CRC64;
     MAEKTNGAAA PNGAADAPKS SPEQAQDVAD VPVTDENGEQ IPEDTVLSLT IVLPQNSEKI
     PIAVSPHEQV HEVRQSIIEM PNALQYSCFH LEHKGERIND FAQISEIKDI ADGDEIHLVE
     DPYTEKEARI HLIRVRELIG AAGDRTDSVQ GILPGLSVYD TVAAEARNAT EVGEYEFNAG
     PNVKALLPKE NDPQPKTVKA IQVSPWNPPP AHFRQKGHLL YLIITTNEGE QFQITGHVGG
     FFVNKSSNSK FDPLPRAGPK AYAAHSLLTL IEQLSPAFSK AFAELQEYTN QREPLSTFQI
     TNAIPAAPWL VPSANSAACT HTPDITRTQE SFLVSGVENT DTLRDWNEEF QSAKELPKDG
     VQDRVFRERL ISKLFADYND AAARGAVLVA RGEVAPLNPT EGKDAQIFVY NNVFFSFGAD
     GVGTFTSEGG DEAARVATAK DVSGVKLVNQ LDIDGLYTPG TVVVDYLGKR IVGQSIVPGI
     FKQREPGENQ IDYGAVDGKD LVATDERFVP QFQKLSKALK VKPHAVWDKE GKRHDLEGSV
     ETKGLVGTDG RKYVLDLYRI TPLDVSWQEE VEAESDAPEY PHRMTVLRPE LVELFVRQKM
     REWVSSEVAK RGQAKKDQAA VEEKKEAKAE SEEDSDSSSE EESSSDESDS EESSSDEDEE
     EEKKPKKKSV PKKAAKKEEV KEEKKDEKEA SSDRIDVSDF SFTLNPDVFS GQVPQTDAEK
     EAMAADEKDV RDACEYLRKT AIPDLLNDLR ESEISFPMDG QSLSRLLHKR GINLRYLGQI
     ATASDGPRLQ CLKEVSVREM IARGFKHVAA KHLRYLPLPL TSSCISHLLN CLLGTAFNAK
     PTAEIDPSIR SLYDDADLAF ENVTPEILRT AIQEEVARRF RYTLASDWYN NLPHLHMLRE
     VCLKLGIQMQ HKEFIFTAEG AASQPAPVPV TNGNGNAPAE GSKKNKKKKK AARDTSPDSV
     TSSSTIPHTF VPDDIINVVP IVKDSSPRSV LAEEALEAGR ISILQNQRKI GQELLLESLS
     LHEQIYGILH PEVARVYHSL AMLYFQLEEK DAAVELARKA VIVAERTIGV DSQETLLDYL
     NLSLFLYQLG DSKQALEFTK HALNMWKIIY GPDHPDMITT INNAAVMLQQ LKEYHESRRW
     FEEALRICEV VFGRQSVNSA TLLFQLAQAL ALDQEPKAAV VKMKESYNIF LAELGPEDKN
     TKEAEGWLEQ LTTNAVSIAK HAKDVEERRL RAGIRFTPRA GAIGSTSTAA NKVAKSEIER
     PAAASSMDSR SIDELLKFIE GTDKQKKPAA KKRTGRANPK RRGAEPVSTK A