CLU_PHANO
ID CLU_PHANO Reviewed; 1280 AA.
AC Q0U0H7;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 2.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Clustered mitochondria protein homolog {ECO:0000255|HAMAP-Rule:MF_03013};
DE AltName: Full=Protein TIF31 homolog {ECO:0000255|HAMAP-Rule:MF_03013};
GN Name=CLU1 {ECO:0000255|HAMAP-Rule:MF_03013};
GN Synonyms=TIF31 {ECO:0000255|HAMAP-Rule:MF_03013}; ORFNames=SNOG_14691;
OS Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS blotch fungus) (Parastagonospora nodorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC Parastagonospora.
OX NCBI_TaxID=321614;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT analysis of the wheat pathogen Stagonospora nodorum.";
RL Plant Cell 19:3347-3368(2007).
CC -!- FUNCTION: mRNA-binding protein involved in proper cytoplasmic
CC distribution of mitochondria. {ECO:0000255|HAMAP-Rule:MF_03013}.
CC -!- SUBUNIT: May associate with the eukaryotic translation initiation
CC factor 3 (eIF-3) complex. {ECO:0000255|HAMAP-Rule:MF_03013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03013}.
CC -!- SIMILARITY: Belongs to the CLU family. {ECO:0000255|HAMAP-
CC Rule:MF_03013}.
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DR EMBL; CH445357; EAT77883.2; -; Genomic_DNA.
DR RefSeq; XP_001804874.1; XM_001804822.1.
DR AlphaFoldDB; Q0U0H7; -.
DR SMR; Q0U0H7; -.
DR STRING; 13684.SNOT_14691; -.
DR PRIDE; Q0U0H7; -.
DR EnsemblFungi; SNOT_14691; SNOT_14691; SNOG_14691.
DR GeneID; 5981800; -.
DR KEGG; pno:SNOG_14691; -.
DR eggNOG; KOG1839; Eukaryota.
DR HOGENOM; CLU_003256_2_0_1; -.
DR InParanoid; Q0U0H7; -.
DR OrthoDB; 60958at2759; -.
DR Proteomes; UP000001055; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0048312; P:intracellular distribution of mitochondria; IBA:GO_Central.
DR CDD; cd15466; CLU-central; 1.
DR Gene3D; 1.25.40.10; -; 2.
DR HAMAP; MF_03013; CLU; 1.
DR InterPro; IPR033646; CLU-central.
DR InterPro; IPR025697; CLU_dom.
DR InterPro; IPR028275; CLU_N.
DR InterPro; IPR027523; CLU_prot.
DR InterPro; IPR023231; GSKIP_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12601; PTHR12601; 1.
DR Pfam; PF13236; CLU; 1.
DR Pfam; PF15044; CLU_N; 1.
DR Pfam; PF12807; eIF3_p135; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF103107; SSF103107; 1.
DR SUPFAM; SSF48452; SSF48452; 2.
DR PROSITE; PS51823; CLU; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..1280
FT /note="Clustered mitochondria protein homolog"
FT /id="PRO_0000366411"
FT DOMAIN 338..582
FT /note="Clu"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01167"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 633..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 905..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1214..1280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..185
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..669
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 905..927
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1244..1267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1280 AA; 141616 MW; CBB48667DA16B14E CRC64;
MAASSNDASK SAMANSNVTT EVAQTPSKEQ DVNGEVEATE EDGANGQLPD NIFQIKIKLP
HEPFEIPMTI STAEQVQDLR QSIIEMPNTF QYSCFHLEHK GQRINDFVDL SEVPELGPDS
VLEVKEDPYN EKEARLHVIR VRELIGAAGD RTDALHGIMA GLSLHDTVGL DQSGKPKEDG
PEQSPLADYD FKSSGAIKNL LPPPQEPAPK CIKSIALSAW NPPPYHLRTK GHLLYLVAMT
NENEQHHITS HVTGFYVNKS SNASFDPAPR QGPKALHAHS LLTLLEKLSP SFEASFQQLL
EHNAKKELLT IFQLSNAIPA NPWLVPPPTS SLTTHQPDLA RTQESYLISG VENTDTLRDW
NEEFQSTREM PKEAVHDRVF RERLTSKLFA DYNDAATRGA MLVARGEIAP LNPTEAKDAQ
IFVYNNIFYS FGADGVGTFG TEGGDEAARV AVGKDVIGVR AVNNLDIPNL FTSGTVVVDF
LGKRIVGQSI VPGIFKQRDP GEHQIDYGAV EGKEIVADDK SFVPLFEQLS KALRVKKHPV
WDKDNVRHEL EGSVETKGLI GTDGRRYALD LYRLTPLDVA WIEAHWSEPS KDEDAKPSEK
NYPHRMATLR PELVESYGRL KLREYVKNEI DKKANKARGG RRRLPKAQKK ADAGKEVDGE
KKAEAEPEQD RVDISGFSFA LNPDVFSGQT PQSDEDKAEW AKDEAEVRAA CDHLQTEVIP
RMITELKDGE VGFPMDGQSL SSLLHKRGVN IRYLGKIAEL SDKPDPRLQA LKRLIVQEMI
ARGFKHFANS KLRNVSAPFS AACVAHLLNC LLGADANAKP VAECDEEIKR MISTPEDDFS
FEKLTPESLK KEVIAQIALR YRYDLGESWV ESGKELQLLR EVSLKLGLQL QTRQYGFTKE
TLTNGAAVPT PAAPQTNGSS TSSKKKKNKT ITPPRADSPA VSLPSQTFHA DDILNIVPVI
KEASPKSLLA EEALEAGRMS VAQDQKELGQ ELLLESLQLH EQIYGVLHPE VARAYHTLSN
LLFNLDDKAS ALELAHKAVI VSERTLGVDH ADTVLAYLNL GLFEHASGNT KAALVYVRHA
LELWKIIYGA DHPDSITTLN NAAVMLQAMK QYHESRIWFE ASLAICEDVS GKTSINTATL
LFQTAQALAL DKDMRGAVNR MRESYNIFKD VLGAEDRNTK EAESWLEQLT QSAVSQAKQL
NDLAKGRIRR IQLTGRNPLR PAAATPSVSD AAAAAGGQRT GTGRVDQRKI EDLLKYIEGE
SSKTPTKKRT QNPRKRTQKP
