CLU_USTMA
ID CLU_USTMA Reviewed; 1404 AA.
AC Q4PA50; A0A0D1DY64;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Clustered mitochondria protein homolog {ECO:0000255|HAMAP-Rule:MF_03013};
DE AltName: Full=Protein TIF31 homolog {ECO:0000255|HAMAP-Rule:MF_03013};
GN Name=CLU1 {ECO:0000255|HAMAP-Rule:MF_03013};
OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=237631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=521 / FGSC 9021;
RX PubMed=17080091; DOI=10.1038/nature05248;
RA Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA Birren B.W.;
RT "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT maydis.";
RL Nature 444:97-101(2006).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=521 / FGSC 9021;
RA Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: mRNA-binding protein involved in proper cytoplasmic
CC distribution of mitochondria. {ECO:0000255|HAMAP-Rule:MF_03013}.
CC -!- SUBUNIT: May associate with the eukaryotic translation initiation
CC factor 3 (eIF-3) complex. {ECO:0000255|HAMAP-Rule:MF_03013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03013}.
CC -!- SIMILARITY: Belongs to the CLU family. {ECO:0000255|HAMAP-
CC Rule:MF_03013}.
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DR EMBL; CM003146; KIS69034.1; -; Genomic_DNA.
DR RefSeq; XP_011389394.1; XM_011391092.1.
DR AlphaFoldDB; Q4PA50; -.
DR SMR; Q4PA50; -.
DR STRING; 5270.UM03013P0; -.
DR EnsemblFungi; KIS69034; KIS69034; UMAG_03013.
DR GeneID; 23563604; -.
DR KEGG; uma:UMAG_03013; -.
DR VEuPathDB; FungiDB:UMAG_03013; -.
DR eggNOG; KOG1839; Eukaryota.
DR HOGENOM; CLU_003256_2_0_1; -.
DR InParanoid; Q4PA50; -.
DR OMA; VSGFYVN; -.
DR OrthoDB; 60958at2759; -.
DR Proteomes; UP000000561; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0048312; P:intracellular distribution of mitochondria; IBA:GO_Central.
DR CDD; cd15466; CLU-central; 1.
DR Gene3D; 1.25.40.10; -; 1.
DR HAMAP; MF_03013; CLU; 1.
DR InterPro; IPR033646; CLU-central.
DR InterPro; IPR025697; CLU_dom.
DR InterPro; IPR028275; CLU_N.
DR InterPro; IPR027523; CLU_prot.
DR InterPro; IPR023231; GSKIP_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR12601; PTHR12601; 1.
DR Pfam; PF13236; CLU; 1.
DR Pfam; PF15044; CLU_N; 1.
DR Pfam; PF12807; eIF3_p135; 1.
DR SUPFAM; SSF103107; SSF103107; 1.
DR SUPFAM; SSF48452; SSF48452; 1.
DR PROSITE; PS51823; CLU; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..1404
FT /note="Clustered mitochondria protein homolog"
FT /id="PRO_0000366415"
FT DOMAIN 357..646
FT /note="Clu"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01167"
FT REGION 528..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 996..1046
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1337..1372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..555
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 706..722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1404 AA; 153208 MW; FFB17EB75FD327C4 CRC64;
MDPVTQAPAP EGVDAPEIDE SLQPFEINLY LPKRPLIPSA AASANGLPET PSPLKVAVTP
QETLNDLRVT ITDSPEGYWL GAFCFRKPLA SPNSTAKGGK VQLGERVPEW TELREIFEGV
DKDKRELHVT HVPFNEADAR AHVQRLRDLL SGGAADPSAI GVDAALSVQD AVRNPQEWQQ
DAARQNANGR AVTKKGVNDA AEASSELPLP LVDWAGWPSV TSIDLIPQVA RRPRQLPVCV
RQLSLASWNP PPQHCKLNGH LLYLQVGTLE GEVIFVTAST HGFYVNRSSG ARFDPSPRPD
GQDFASCSLF DLLCGFSPLF LSSFSKLFND PLSSRDYFSA VPVTNALPAF PWLARNHTHH
ADALRSQAAF LLTGATSADA LEGTRDWNDE LQSARELPRT TLSERLMRDR VLNRIYSEFT
QAAARAIPKV AAGEVQAMNP MDKRDAQMFI VNNLFISKGA DGVDLYPHMG GDEAAHVAVG
KDVQGVKTLN SLDVGGLCLL GTIVVDWKGE RWVAQSVVPG LFRRRDDADE LPEADGETTE
LAEAAPEKKS PEAKLAQSNK ADLNDDTQVV YGGVEGPEVI RDNAAFHKLF HQVAQTLHLN
EHQVEDAKGI KHSLWLSVDS KGLRGADGRR YVLDLARLNP VDINWLENDI DGAIHGSSSS
PNQDAHYPHR MTLLRPELLE IYWDSEFRKW ARAKLAARQE AKAAKDAKAK EAASKEDGEK
TEAPEVEAEE PERLDSSEFK LTFNPDAFVE FKVADTLAEE HSKVITPITD ESDASIAAVR
QASDFLRKVA IPRFVTDVAA GLFTAADGGA LSRQMHARGI NVRYLGYVAR LCSPEAKQEL
DQELIQKAGP GHEGFLNAFR LTVLQEMVLR ASKRVLRGLI RDVEQVNVAA CVSHFLNCLV
GDKVNAHPKA RPSVTPLSDV ADAAWTKLTP ETLREELKAE IRKRFRFELP ASFFEQELRR
AQLLREVALR TGIQLQLQEY VLEGKLADAD GVVSDGCHGE SQTNGNTTNK KNSKGKKKGG
NEQQNGVKKS NVGAAAAKPT KAARATSFEP EDVLNLVPMV KDSTPKSTLA EEAFEAGRIS
ISRGDRELGL ELLLEGVSFH EQVYGLVHPE VARCYALFAT IVHHLAGVAA MERAESINQA
KSENKEITEA DLPVVNEHLS MANAVRYQRQ AVTVSERTLG LDHPETLNQY MNLAVLERSA
GNTRESLLCQ RRVLELWSLL HGQHHPDCIN ALSNVALTLQ NARLFEASLR VYRSAHELAL
TLFGADSIHT ANLAHELSQA YTLAGDLKTA LAVEKEAWRV FEERLGKDDA QTKESEAFCS
SLAASAVRVA KLEKEASERQ ARLPASRRGN SNAGGGAAAI TGAGTTASGN GTANKSLDEI
VRFIQGGSNG SVAKAKGKSK ASRK
