ID   CM17_CONBU              Reviewed;          29 AA.
AC   P0CY74;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 18.
DE   RecName: Full=Conotoxin Bu17;
DE   Flags: Fragment;
OS   Conus bullatus (Bubble cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Textilia.
OX   NCBI_TaxID=89438;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom duct;
RX   PubMed=21266071; DOI=10.1186/1471-2164-12-60;
RA   Hu H., Bandyopadhyay P.K., Olivera B.M., Yandell M.;
RT   "Characterization of the Conus bullatus genome and its venom-duct
RT   transcriptome.";
RL   BMC Genomics 12:60-60(2011).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC   -!- DOMAIN: The cysteine framework is III (CC-C-C-CC). Classified in the M-
CC       5 branch, since 5 residues stand between the fourth and the fifth
CC       cysteine residues.
CC   -!- SIMILARITY: Belongs to the conotoxin M superfamily. {ECO:0000305}.
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DR   AlphaFoldDB; P0CY74; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0099106; F:ion channel regulator activity; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Amidation; Disulfide bond; Ion channel impairing toxin; Neurotoxin;
KW   Secreted; Toxin.
FT   PEPTIDE         <1..26
FT                   /note="Conotoxin Bu17"
FT                   /id="PRO_0000409964"
FT   MOD_RES         26
FT                   /note="Cysteine amide"
FT                   /evidence="ECO:0000250"
FT   DISULFID        4..19
FT                   /evidence="ECO:0000250"
FT   DISULFID        5..25
FT                   /evidence="ECO:0000250"
FT   DISULFID        15..26
FT                   /evidence="ECO:0000250"
FT   NON_TER         1
SQ   SEQUENCE   29 AA;  3408 MW;  F5B5A3CC9B2B8775 CRC64;
     GLYCCQPKPN GQMMCNRWCE INSRCCGRR