ID   CM34_CONPE              Reviewed;          36 AA.
AC   Q9BP43;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Conotoxin PnMLKMF-01;
DE   Flags: Precursor; Fragment;
OS   Conus pennaceus (Feathered cone) (Conus episcopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Darioconus.
OX   NCBI_TaxID=37335;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom duct;
RX   PubMed=11158371; DOI=10.1093/oxfordjournals.molbev.a003786;
RA   Conticello S.G., Gilad Y., Avidan N., Ben-Asher E., Levy Z., Fainzilber M.;
RT   "Mechanisms for evolving hypervariability: the case of conopeptides.";
RL   Mol. Biol. Evol. 18:120-131(2001).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000305|PubMed:11158371}.
CC   -!- DOMAIN: The cysteine framework is III (CC-C-C-CC). Classified in the M-
CC       1 branch, since 1 residue stands between the fourth and the fifth
CC       cysteine residues. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the conotoxin M superfamily. {ECO:0000305}.
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DR   EMBL; AF215130; AAG60535.1; -; mRNA.
DR   AlphaFoldDB; Q9BP43; -.
DR   ConoServer; 791; Pn3.4 precursor.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Neurotoxin; Secreted; Toxin.
FT   PROPEP          <1..16
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000404882"
FT   PEPTIDE         17..36
FT                   /note="Conotoxin PnMLKMF-01"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000404883"
FT   DISULFID        21..33
FT                   /evidence="ECO:0000250|UniProtKB:Q5EHP3"
FT   DISULFID        22..31
FT                   /evidence="ECO:0000250|UniProtKB:Q5EHP3"
FT   DISULFID        27..34
FT                   /evidence="ECO:0000250|UniProtKB:Q5EHP3"
FT   NON_TER         1
SQ   SEQUENCE   36 AA;  3683 MW;  04C74E40FF71141C CRC64;
     DDNPGGASGK FMNVLKGQPL CCPFGGCHEL CHCCGS