CMC4_LACTC
ID CMC4_LACTC Reviewed; 77 AA.
AC C5E268;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=Cx9C motif-containing protein 4, mitochondrial;
GN Name=CMC4; OrderedLocusNames=KLTH0H02552g;
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000250}.
CC Note=Imported into the mitochondria via the mitochondrial disulfide
CC relay system. {ECO:0000250}.
CC -!- DOMAIN: The twin Cx9C motifs are involved in the recognition by the
CC mitochondrial disulfide relay system. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CMC4 family. {ECO:0000305}.
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DR EMBL; CU928180; CAR30129.1; -; Genomic_DNA.
DR RefSeq; XP_002555991.1; XM_002555945.1.
DR AlphaFoldDB; C5E268; -.
DR SMR; C5E268; -.
DR STRING; 559295.C5E268; -.
DR EnsemblFungi; CAR30129; CAR30129; KLTH0H02552g.
DR GeneID; 8294304; -.
DR KEGG; lth:KLTH0H02552g; -.
DR eggNOG; ENOG502S7M4; Eukaryota.
DR HOGENOM; CLU_177210_0_1_1; -.
DR InParanoid; C5E268; -.
DR OMA; CAIQNCI; -.
DR OrthoDB; 1633942at2759; -.
DR Proteomes; UP000002036; Chromosome H.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR InterPro; IPR009069; Cys_alpha_HP_mot_SF.
DR InterPro; IPR027179; MTCP1.
DR PANTHER; PTHR15590; PTHR15590; 1.
DR Pfam; PF08991; MTCP1; 1.
DR SUPFAM; SSF47072; SSF47072; 1.
DR PROSITE; PS51808; CHCH; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Mitochondrion; Reference proteome; Repeat.
FT CHAIN 1..77
FT /note="Cx9C motif-containing protein 4, mitochondrial"
FT /id="PRO_0000408575"
FT DOMAIN 2..44
FT /note="CHCH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 5..15
FT /note="Cx9C motif 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 26..36
FT /note="Cx9C motif 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 5..36
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 15..26
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ SEQUENCE 77 AA; 8539 MW; C5840798EC7691B3 CRC64;
MTDPCKPQAC AIQGCLTKTG FDESKCSHLI DSLYECCSKF YNERGADART PCCPVPSLLR
LKLEQRACGP LDAKRVR
