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CMCC2_CONPO
ID   CMCC2_CONPO             Reviewed;          65 AA.
AC   D5L5Q8;
DT   10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT   15-JUN-2010, sequence version 1.
DT   25-MAY-2022, entry version 20.
DE   RecName: Full=Conopeptide Vt3.2;
DE   Flags: Precursor; Fragment;
OS   Conus planorbis (Planorbis cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Strategoconus.
OX   NCBI_TaxID=97183;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom duct;
RX   PubMed=20307606; DOI=10.1016/j.peptides.2010.03.010;
RA   Wu X.-C., Zhou M., Peng C., Shao X.-X., Guo Z.-Y., Chi C.-W.;
RT   "Novel conopeptides in a form of disulfide-crosslinked dimer.";
RL   Peptides 31:1001-1006(2010).
CC   -!- SUBUNIT: Homodimer; disulfide-linked. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC   -!- DOMAIN: The cysteine framework is C-C.
CC   -!- SIMILARITY: Belongs to the conotoxin M superfamily. {ECO:0000305}.
CC   -!- CAUTION: The name Vt3.2 given by the authors is incorrect, since the
CC       first number indicates a cysteine framework III which does not
CC       correspond to this cysteine framework. {ECO:0000305|PubMed:20307606}.
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DR   EMBL; GU784863; ADE35089.1; -; mRNA.
DR   AlphaFoldDB; D5L5Q8; -.
DR   ConoServer; 4060; Vt3.2 precursor.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Amidation; Cleavage on pair of basic residues; Disulfide bond; Secreted;
KW   Signal; Toxin.
FT   SIGNAL          <1..12
FT                   /evidence="ECO:0000255"
FT   PROPEP          13..48
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000397203"
FT   PEPTIDE         52..64
FT                   /note="Conopeptide Vt3.2"
FT                   /id="PRO_0000397204"
FT   MOD_RES         64
FT                   /note="Serine amide"
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
SQ   SEQUENCE   65 AA;  7547 MW;  033CC2385F2713B3 CRC64;
     LLFPLATLQL NADQPVERNA ENIQDLNPDK RFIFMPVPRR RGPYGSVHRR RGPYRRHGNC
     FCPSG
 
 
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