CMLN1_CUPSE
ID CMLN1_CUPSE Reviewed; 63 AA.
AC C0HLQ2;
DT 10-FEB-2021, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2021, sequence version 1.
DT 25-MAY-2022, entry version 4.
DE RecName: Full=Cypmaclein {ECO:0000250|UniProtKB:C0HLL6};
DE AltName: Allergen=Cup s 7 {ECO:0000303|PubMed:32506709};
OS Cupressus sempervirens (Italian cypress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Pinopsida; Pinidae; Conifers II; Cupressales; Cupressaceae;
OC Cupressus.
OX NCBI_TaxID=13469;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, SYNTHESIS, TISSUE SPECIFICITY, MASS SPECTROMETRY, AND
RP ALLERGEN.
RC TISSUE=Pollen {ECO:0000303|PubMed:32506709};
RX PubMed=32506709; DOI=10.1111/cea.13675;
RA Ehrenberg A.E., Klingebiel C., Oestling J., Larsson H., Mattsson L.,
RA Vitte J., Lidholm J.;
RT "Characterization of a 7 kDa pollen allergen belonging to the gibberellin-
RT regulated protein family from three Cupressaceae species.";
RL Clin. Exp. Allergy 50:964-972(2020).
CC -!- TISSUE SPECIFICITY: Expressed in pollen (at protein level).
CC {ECO:0000269|PubMed:32506709}.
CC -!- MASS SPECTROMETRY: Mass=6828.98; Method=Electrospray;
CC Evidence={ECO:0000269|PubMed:32506709};
CC -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE in 32% of
CC 88 patients with cypress pollen sensitivity.
CC {ECO:0000269|PubMed:32506709}.
CC -!- SIMILARITY: Belongs to the GASA family. {ECO:0000305}.
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DR AlphaFoldDB; C0HLQ2; -.
DR SMR; C0HLQ2; -.
DR InterPro; IPR003854; GASA.
DR Pfam; PF02704; GASA; 1.
PE 1: Evidence at protein level;
KW Allergen; Direct protein sequencing.
FT CHAIN 1..63
FT /note="Cypmaclein"
FT /id="PRO_0000451766"
SQ SEQUENCE 63 AA; 6834 MW; EDE0EE49BA1A78E0 CRC64;
AQIDCDKECN RRCSKASAHD RCLKYCGICC EKCHCVPPGT AGNEDVCPCY ANLKNSKGGH
KCP