ID   CMPC_SYNP6              Reviewed;         663 AA.
AC   Q5MZ54;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Bicarbonate transport ATP-binding protein CmpC;
DE            EC=7.6.2.-;
GN   Name=cmpC; OrderedLocusNames=syc2476_d;
OS   Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis
OS   nidulans).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=269084;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RX   PubMed=17211581; DOI=10.1007/s11120-006-9122-4;
RA   Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M.,
RA   Kanehisa M., Omata T., Sugiura M., Sugita M.;
RT   "Complete nucleotide sequence of the freshwater unicellular cyanobacterium
RT   Synechococcus elongatus PCC 6301 chromosome: gene content and
RT   organization.";
RL   Photosyn. Res. 93:55-67(2007).
CC   -!- FUNCTION: Part of the ABC transporter complex CmpABCD involved in
CC       bicarbonate transport. Responsible for energy coupling to the transport
CC       system (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (CmpC and
CC       CmpD), a transmembrane protein (CmpB) and a solute-binding protein
CC       (CmpA). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral
CC       membrane protein {ECO:0000305}.
CC   -!- INDUCTION: By carbon dioxide-limited conditions, probably via CmpR.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.
CC       {ECO:0000305}.
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DR   EMBL; AP008231; BAD80666.1; -; Genomic_DNA.
DR   RefSeq; WP_011244786.1; NC_006576.1.
DR   AlphaFoldDB; Q5MZ54; -.
DR   SMR; Q5MZ54; -.
DR   STRING; 269084.syc2476_d; -.
DR   EnsemblBacteria; BAD80666; BAD80666; syc2476_d.
DR   KEGG; syc:syc2476_d; -.
DR   eggNOG; COG0715; Bacteria.
DR   eggNOG; COG1116; Bacteria.
DR   OMA; LTMTRNG; -.
DR   Proteomes; UP000001175; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015112; F:nitrate transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd13553; PBP2_NrtA_CpmA_like; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR005890; NO3_transporter_ATP-bd.
DR   InterPro; IPR044527; NrtA/CpmA_ABC-bd_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01184; ntrCD; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW   Nucleotide-binding; Translocase; Transport.
FT   CHAIN           1..663
FT                   /note="Bicarbonate transport ATP-binding protein CmpC"
FT                   /id="PRO_0000341955"
FT   DOMAIN          5..239
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   REGION          281..663
FT                   /note="CmpA-like"
FT   BINDING         42..49
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   663 AA;  73492 MW;  C744FEF286BCB15A CRC64;
     MSLFVAVENI EKSFPLSGGN EYLALKGIDL EIKQGEFISL IGHSGCGKST LLNLIAGLEL
     PTDGAVSLEG QQITAPGPDR MVVFQNYSLF PWLTVRENIA LAVDEVLRDL PKEERQAIVE
     EHIQLVGLGH AADKPPAQLS GGMKQRVAIA RGLATRPKLL LLDEPFGALD ALTRGNLQEK
     LMQICEENHV TAVMVTHDVD EAVLLSDRIV MLTNGPGSKI GGILEVDIPR PRKRMDVVHH
     PSYYSLRSEI IYFLNQQKRV KKLNARKVTT VARHGLEKVN LEIGYVPLMA CAPLVVAQEK
     AFFAKHGLDE VSLVRETSWR GIVDGLTENY LDAAQMPAGM PVWMSVGGQG GSPLPIVSSL
     TMSRNGNGIT LSKALYDEGI QTVDDFRNLL RSTADKQHIM GIVHPASMHN LLLRYWLAAN
     QIDPDRDVQL RTIPPAQMVA DLKDGTIDGY CIGEPWNAWA AQKEIGFTIA SDLEIWNGHP
     GKVLGVREDW ANRYPNSHVA LVKALLEACQ YCEDPANWDE LRELLSDRRY LSCPKEYIQF
     SQSTADDLAV PHHRFAGAGV NRPSRTEHLW MMTQLARWGD VPFPRNWVEI LERVCRVGVF
     STAARELGLS EVVNYQRSTP VELFDGVPFN AEDPIAYLNS LPIHRDFSVA EIALDQPRPI
     AAA