ID   CMPC_SYNY3              Reviewed;         667 AA.
AC   Q55462;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 135.
DE   RecName: Full=Bicarbonate transport ATP-binding protein CmpC;
DE            EC=7.6.2.-;
GN   Name=cmpC; OrderedLocusNames=slr0043;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
RN   [2]
RP   REGULATION BY CMPR.
RX   PubMed=11222586; DOI=10.1128/jb.183.6.1891-1898.2001;
RA   Omata T., Gohta S., Takahashi Y., Harano Y., Maeda S.;
RT   "Involvement of a CbbR homolog in low CO2-induced activation of the
RT   bicarbonate transporter operon in cyanobacteria.";
RL   J. Bacteriol. 183:1891-1898(2001).
CC   -!- FUNCTION: Part of the ABC transporter complex CmpABCD involved in
CC       bicarbonate transport. Responsible for energy coupling to the transport
CC       system (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (CmpC and
CC       CmpD), a transmembrane protein (CmpB) and a solute-binding protein
CC       (CmpA). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral
CC       membrane protein {ECO:0000305}.
CC   -!- INDUCTION: By carbon dioxide-limited conditions, probably via CmpR.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.
CC       {ECO:0000305}.
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DR   EMBL; BA000022; BAA10806.1; -; Genomic_DNA.
DR   PIR; S75959; S75959.
DR   AlphaFoldDB; Q55462; -.
DR   SMR; Q55462; -.
DR   STRING; 1148.1001319; -.
DR   PaxDb; Q55462; -.
DR   EnsemblBacteria; BAA10806; BAA10806; BAA10806.
DR   KEGG; syn:slr0043; -.
DR   eggNOG; COG0715; Bacteria.
DR   eggNOG; COG1116; Bacteria.
DR   InParanoid; Q55462; -.
DR   OMA; LTMTRNG; -.
DR   PhylomeDB; Q55462; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015112; F:nitrate transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd13553; PBP2_NrtA_CpmA_like; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR005890; NO3_transporter_ATP-bd.
DR   InterPro; IPR044527; NrtA/CpmA_ABC-bd_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01184; ntrCD; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW   Nucleotide-binding; Reference proteome; Translocase; Transport.
FT   CHAIN           1..667
FT                   /note="Bicarbonate transport ATP-binding protein CmpC"
FT                   /id="PRO_0000341956"
FT   DOMAIN          5..239
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   REGION          281..667
FT                   /note="CmpA-like"
FT   BINDING         42..49
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   667 AA;  74097 MW;  68D5F41046C91DA1 CRC64;
     MSLFVAVDNI DKVFSLTDGG EYIALKGINL EIKKGEFVSL IGHSGCGKST LLNMIAGLDL
     PSEGIVTLEG QRIKQPGPDK MVIFQNYSLL PWLTVKQNIA LAVDEVMKGA SAAERKAIVE
     EHINLVGLGH AVDKRPGELS GGMKQRVAIA RALAIRPKLL LLDEPFGALD ALTRGNLQEQ
     LMRICEQYQV TAVMVTHDVD EAVLLSDRIV MLTNGPGSNI GGILEVDIPR PRKRMEVVEH
     PSYYSLRSEI IYFLNQQKRI KKLRAKKTTA IARHGLEKVN LELGYVPLVA CAPLVVAQEK
     GFFAKHGLDE VSLVRETSWR GIVDGIAGGY LDGAQMPAGM PTWLTAGGYR EQSIPVVSAL
     TMTRNGNAIT LSKKLYDQGI YTAEDFRQLL LASDGDRHTL GMVHPSSMHN LLLRYWLAAH
     NINPDRDVHL KTIPPAQMVA DLKAGTIDGY CVSEPWNLRA SMEGAGFSIA TDLEIWQNHP
     GKVLGVREDW AIAHPNTHVA LVKALLEACA YCADPNHEME IRELLATRQY LSTNIDYIHL
     GDPEGRTCRL GNPVEYSHHL FFGDQFNRPS RTEHLWMMTQ MARWGDIPFP RNWVEILERV
     CRVGVFSTAA RELGYDVNYQ RQPIALFDGK VFNADDPIAY LNQTVIHRNF TIAEVHLDNP
     TPAPVFA