CMPD_SYNE7
ID CMPD_SYNE7 Reviewed; 278 AA.
AC Q55108; Q31N48;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Bicarbonate transport ATP-binding protein CmpD;
DE EC=7.6.2.-;
GN Name=cmpD; OrderedLocusNames=Synpcc7942_1491;
OS Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans
OS R2).
OC Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX NCBI_TaxID=1140;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Omata T.;
RL Submitted (DEC-1993) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7942 / FACHB-805;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M.,
RA Kyrpides N., Lykidis A., Richardson P.;
RT "Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP FUNCTION IN BICARBONATE TRANSPORT, AND INDUCTION.
RX PubMed=10557362; DOI=10.1073/pnas.96.23.13571;
RA Omata T., Price G.D., Badger M.R., Okamura M., Gohta S., Ogawa T.;
RT "Identification of an ATP-binding cassette transporter involved in
RT bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC
RT 7942.";
RL Proc. Natl. Acad. Sci. U.S.A. 96:13571-13576(1999).
RN [4]
RP REGULATION BY CMPR.
RX PubMed=11222586; DOI=10.1128/jb.183.6.1891-1898.2001;
RA Omata T., Gohta S., Takahashi Y., Harano Y., Maeda S.;
RT "Involvement of a CbbR homolog in low CO2-induced activation of the
RT bicarbonate transporter operon in cyanobacteria.";
RL J. Bacteriol. 183:1891-1898(2001).
CC -!- FUNCTION: Part of the ABC transporter complex CmpABCD involved in
CC bicarbonate transport. Responsible for energy coupling to the transport
CC system (Probable). {ECO:0000305|PubMed:10557362}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (CmpC and
CC CmpD), a transmembrane protein (CmpB) and a solute-binding protein
CC (CmpA). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral
CC membrane protein {ECO:0000305}.
CC -!- INDUCTION: By carbon dioxide-limited conditions, probably via CmpR.
CC {ECO:0000269|PubMed:10557362}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.
CC {ECO:0000305}.
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DR EMBL; D26358; BAA05389.1; -; Genomic_DNA.
DR EMBL; CP000100; ABB57521.1; -; Genomic_DNA.
DR RefSeq; WP_011244787.1; NC_007604.1.
DR AlphaFoldDB; Q55108; -.
DR SMR; Q55108; -.
DR STRING; 1140.Synpcc7942_1491; -.
DR TCDB; 3.A.1.16.3; the atp-binding cassette (abc) superfamily.
DR PRIDE; Q55108; -.
DR EnsemblBacteria; ABB57521; ABB57521; Synpcc7942_1491.
DR KEGG; syf:Synpcc7942_1491; -.
DR eggNOG; COG1116; Bacteria.
DR HOGENOM; CLU_000604_1_22_3; -.
DR OMA; YSLFPWR; -.
DR OrthoDB; 1832232at2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0015112; F:nitrate transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR005890; NO3_transporter_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR01184; ntrCD; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW Nucleotide-binding; Translocase; Transport.
FT CHAIN 1..278
FT /note="Bicarbonate transport ATP-binding protein CmpD"
FT /id="PRO_0000341957"
FT DOMAIN 21..254
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 57..64
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 278 AA; 31541 MW; 3F5B334F26B8460F CRC64;
MQTLRQQQPI VPSSPGHDPF LIVENVSKIY ETPKGPYTVL DGVNLTVQEG EFICVIGHSG
CGKSTLLNMV SGFNQPSHGS VRLKGKEIDR PGPDRMVVFQ NYALLPWMTA YENVYLAVDC
VNPQMREGEK REIVREHLAM VGLTEAAEKK ITQISGGMKQ RVAIARALSI RPEVLILDEP
FGALDAITKE ELQEELLKIW NDHRCTVLMI THDIDEALFL ADRLVMMTNG PAANIGEIMT
IPFPRPRDRE RIMEDPQYYD LRNYALDFLY NRFAHDDE
