ID   CMR1_PHANO              Reviewed;         519 AA.
AC   Q0UYV9;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=DNA damage-binding protein CMR1 {ECO:0000250|UniProtKB:Q12510};
GN   ORFNames=SNOG_03055;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: DNA-binding protein that binds to both single- and double-
CC       stranded DNA. Binds preferentially to UV-damaged DNA. May be involved
CC       in DNA-metabolic processes. {ECO:0000250|UniProtKB:Q12510}.
CC   -!- SIMILARITY: Belongs to the WD repeat DDB2/WDR76 family. {ECO:0000305}.
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DR   EMBL; CH445328; EAT89786.1; -; Genomic_DNA.
DR   RefSeq; XP_001793644.1; XM_001793592.1.
DR   AlphaFoldDB; Q0UYV9; -.
DR   SMR; Q0UYV9; -.
DR   STRING; 13684.SNOT_03055; -.
DR   EnsemblFungi; SNOT_03055; SNOT_03055; SNOG_03055.
DR   GeneID; 5970501; -.
DR   KEGG; pno:SNOG_03055; -.
DR   eggNOG; KOG4328; Eukaryota.
DR   HOGENOM; CLU_017019_1_1_1; -.
DR   InParanoid; Q0UYV9; -.
DR   OMA; TVVRHNC; -.
DR   OrthoDB; 753973at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0000785; C:chromatin; IEA:EnsemblFungi.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR   GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:2000001; P:regulation of DNA damage checkpoint; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR033052; Cmr1/WDR76.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR14773:SF0; PTHR14773:SF0; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA-binding; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..519
FT                   /note="DNA damage-binding protein CMR1"
FT                   /id="PRO_0000351112"
FT   REPEAT          240..280
FT                   /note="WD 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          287..327
FT                   /note="WD 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          331..371
FT                   /note="WD 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          380..420
FT                   /note="WD 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          442..485
FT                   /note="WD 5"
FT                   /evidence="ECO:0000255"
FT   REPEAT          488..519
FT                   /note="WD 6"
FT                   /evidence="ECO:0000255"
FT   REGION          35..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..92
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   519 AA;  57482 MW;  89F18A4015489E1F CRC64;
     MARGKNVELS EYERKRQENI AKTQALLRNL EMEAAEAGLG PTGKSRAAAS SKPRVKKPAP
     KKIKQEDIAP RRTSSRLKGI EADSEKAKRK AEDEYVAIKE ADRAKRQRVS DAFNFSDIVV
     AGKDWNRSGN FLSIGPANPY ERTFDFDDVK ETTDKELRAL REKMSGLQLW EDFEPNEIKI
     TPERIYAMGM HPTTEKPLVF AGDKLGNLGI CDASQKVAEV KQEDDEDADN EGPTITTLKP
     HTRTIHTFQF SPHDSNALYS ASYDSSVRKL DLAKGVAVEV YGPSDPNEDQ PLSGLEISKD
     DANTLYFSTL DGRFGIYDMR TPSDQAELFQ LSEKKIGGFS LHPQQPHLVA TASLDRTLKI
     WDLRKISGKG DSRLPALVGE HESRLSVSHA AWNSAGQVAT ASYDDTIKIH DFSKSAEWAT
     GTALTDADMK PSVVVPHNNQ TGRWVTILRA QWQQFPQDGV QRFCIGNMNR FVDIYTAKGQ
     QLAQLGGDGI TAVPAVAKFH PTLDWVAAGT ASGKLCLWM