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CMS1_MOUSE
ID   CMS1_MOUSE              Reviewed;         276 AA.
AC   Q9CZT6; Q9CY77;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=Protein CMSS1;
DE   AltName: Full=Cms1 ribosomal small subunit homolog;
GN   Name=Cmss1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Embryo;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Mammary gland;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the CMS1 family. {ECO:0000305}.
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DR   EMBL; AK012168; BAB28074.1; -; mRNA.
DR   EMBL; AK019979; BAB31948.1; -; mRNA.
DR   EMBL; BC038891; AAH38891.1; -; mRNA.
DR   CCDS; CCDS37365.1; -.
DR   RefSeq; NP_079875.2; NM_025599.3.
DR   AlphaFoldDB; Q9CZT6; -.
DR   SMR; Q9CZT6; -.
DR   IntAct; Q9CZT6; 1.
DR   MINT; Q9CZT6; -.
DR   STRING; 10090.ENSMUSP00000110011; -.
DR   iPTMnet; Q9CZT6; -.
DR   PhosphoSitePlus; Q9CZT6; -.
DR   EPD; Q9CZT6; -.
DR   MaxQB; Q9CZT6; -.
DR   PaxDb; Q9CZT6; -.
DR   PeptideAtlas; Q9CZT6; -.
DR   PRIDE; Q9CZT6; -.
DR   ProteomicsDB; 285503; -.
DR   Antibodypedia; 50471; 42 antibodies from 11 providers.
DR   DNASU; 66497; -.
DR   Ensembl; ENSMUST00000114371; ENSMUSP00000110011; ENSMUSG00000022748.
DR   GeneID; 66497; -.
DR   KEGG; mmu:66497; -.
DR   UCSC; uc007zng.2; mouse.
DR   CTD; 84319; -.
DR   MGI; MGI:1913747; Cmss1.
DR   VEuPathDB; HostDB:ENSMUSG00000022748; -.
DR   eggNOG; KOG3089; Eukaryota.
DR   GeneTree; ENSGT00390000006574; -.
DR   HOGENOM; CLU_057568_2_0_1; -.
DR   InParanoid; Q9CZT6; -.
DR   OMA; QKQRGIF; -.
DR   OrthoDB; 1520704at2759; -.
DR   PhylomeDB; Q9CZT6; -.
DR   TreeFam; TF329710; -.
DR   BioGRID-ORCS; 66497; 2 hits in 77 CRISPR screens.
DR   ChiTaRS; Cmss1; mouse.
DR   PRO; PR:Q9CZT6; -.
DR   Proteomes; UP000000589; Chromosome 16.
DR   RNAct; Q9CZT6; protein.
DR   Bgee; ENSMUSG00000022748; Expressed in interventricular septum and 227 other tissues.
DR   ExpressionAtlas; Q9CZT6; baseline and differential.
DR   Genevisible; Q9CZT6; MM.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR032704; Cms1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24030; PTHR24030; 1.
DR   Pfam; PF14617; CMS1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   2: Evidence at transcript level;
KW   Methylation; Phosphoprotein; Reference proteome.
FT   CHAIN           1..276
FT                   /note="Protein CMSS1"
FT                   /id="PRO_0000239015"
FT   REGION          1..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         19
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5FVR6"
FT   MOD_RES         23
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5FVR6"
FT   MOD_RES         164
FT                   /note="Omega-N-methylarginine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BQ75"
FT   MOD_RES         209
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BQ75"
FT   CONFLICT        19
FT                   /note="S -> R (in Ref. 1; BAB31948)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   276 AA;  31594 MW;  964B9F166F962097 CRC64;
     MADDLGDEWW ENQPAAASSP EQSGGEEGGD TEMTQQDTAP VPEKTQQPTE CFLTQTKEPK
     AEDSRKTRKW KKKKISDILA KSEPKPGTPE DLQKLIRDHY SSSRSVIELE ELHLPDSCFL
     KANDLTHSLS SYLKEICPKW VKLRKTHNEK KSVLMLILCS SAVRALELIR SLTAFKGDAK
     VMKLFAKHIK VQEQVKLLEK RVIHLGVGTP GRIKELVKQD GLHLNPLKFL VFDWNWRDQK
     LRRMMDIPEI RKEVFELLDM GVFSLCKSDS LKLGLF
 
 
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